Apply Topically
A Practical Guide to Formulating Topical Application

The conceptualization and formulation of skin care products intended for topical use is a multifaceted and evolving area of science. Formulators must account for myriad skin types, as well as a very temperamental retail market. This book offers practical approach to the formulation chemist’s day-to-day endeavors by: addressing the innumerable challenges facing the chemist both in design and at bench, such as formulating with/for specific properties; offering valuable “tips” to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems; exploring the advantages and limitations of raw materials; addressing scale-up and pilot production process and concerns and much more.

Dr. Dayan, whose history in the skin care industry includes more than 150 publication credits and an In-cosmetics Gold Award for product innovation, has endeavored to bring you the ultimate handbook on topical product development. This book includes exclusive expert examination and reportage from industry icons such as Roger L. McMullen, Paul Thau, Hemi Nae, Ada Polla, Howard Epstein, Joseph Albanese, Mark Chandler, Steve Herman, Gary Kelm, Patricia Aikens, and Sam Shefer, along with many others.

Explore and examine the following Chapter Sections:

Preliminary Considerations and Selection of Raw Materials

Formulation, Processing and Production Techniques

Testing and Measurements Methods

Sensory and Elegancy

Stability and Preservation

Color Cosmetics

Sunscreens

SECTION I: Preliminary Considerations and Selection of Raw Materials

Chapter 1. Pre-formulation Design and Considerations by Howard Epstein, PhD

Chapter 2. The Use of Thickeners in Topically Applied Formulations by Jed Riemer and Tom Russo

Chapter 3. The Incorporation of Delivery Systems into Topical Formulations: A Case Study on the Use of Salicylic Acid for Acne Treatment by Nripen S. Sharma, PhD; Bryan Grossman; and Sam Shefer, PhD

Chapter 4. Formulating Skin Care Products with Silicones: Approaches and Strategies by Bartley Maxon and Michael Starch

Chapter 5. The Use of Corn-derived Ingredients in Personal Care Applications by Cindy Yu

SECTION II: Formulation, Processing and Production Techniques

Chapter 6. Emulsions and their Characterization by Texture Profile Analysis by Roger L. McMullen, Mihaela Gorcea, and Susan Chen

Chapter 7. High Internal Phase Water-in-oil Emulsions by Paul Thau

Chapter 8. Manufacturing Topical Formulations: Scale-up from Lab to Pilot Production by Michael Kimball

Chapter 9. Foam: A Unique Delivery Vehicle for Topically Applied Formulations by Dov Tamarkin, PhD

SECTION III: Testing and Measurements Methods

Chapter 10. Using Experimental Design to Optimize Formulations by Joseph Albanese

Chapter 11. Rheological Properties of Topical Formulations by Hemi Nae, PhD

Chapter 12. Viscosity Measurement For Topically Applied Formulations by Daphne Benderly, PhD

Chapter 13. Fourier Transform Infrared (FTIR) Spectroscopic Imaging Analysis of Topical Formulations by Samuel Gourion-Arsiquand, Joel Coret, and David J. Moore

SECTION IV: Sensory and Elegancy

Chapter 14. Creating Appealing Topically Applied Formulations: Linking Physical Aspects to Marketing Psychology by J. Mark Chandler

Chapter 15. The Use of Fragrance in Topically Applied Formulations by Steve Herman

SECTION V: Stability and Preservation

Chapter 16. Stability Testing for Topical Formulation Development by Gary R. Kelm, PhD

Chapter 17. Preservation of Topical Formulations: An Historical and Practical Overview by Slawomir Paul Cebulski

Chapter 18. Microbiological Stability for Skin Care Formulations by Kausar Malik

SECTION VI: Color Cosmetics

Chapter 19. Lip Care Product Formulation Strategies by Daniel Sango and David Binder

Chapter 20. Formulation of Nail Care Products by Robert W. Sandewicz

SECTION VII: Sunscreens

Chapter 21. Formulation of Sunscreens in the United States by Patricia Aikens

Chapter 22. Formulating a Day Cream with SPF: A Case Study by Anne Pouillot, MS; Rachel Ametsitsi, MS; and Ada S. Polla, MBA

Glossary of Terms

Author Biographies

Index