Advances in Physical Organic Chemistry

Advances in Physical Organic Chemistry, Volume 51, the latest release in the series, is the definitive resource for authoritative reviews of work in physical organic chemistry. It provides a valuable source of information for not only physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. Its hallmark is a quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

1. The Factors Determining Reactivity in Nucleophilic SubstitutionEinar Uggerud2. Negative Ion Photoelectron Spectroscopy and Its Use in Investigating the Transition States for Some Organic ReactionsWeston T. Borden3. Probing Transition State Analogy in Glycoside Hydrolase CatalysisCinzia Colombo and Andrew J. Bennet4. Phosphate Ester Hydrolysis: The Path From Mechanistic Investigation to the Realization of Artificial EnzymesMarta Diez-Castellnou, Alvaro Martinez and Fabrizio Mancin5. Physicochemical Aspects of Aqueous and Non-aqueous Approaches to the Preparation of Nucleosides, Nucleotides and Phosphate Ester MimicsDavid R.W. Hodgson

• Reviews the application of quantitative and mathematical methods to help readers understand chemical problems
• Provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry
• Covers organic, organometallic, bioorganic, enzymes, and materials topics
• Presents the only regularly published resource for reviews in physical organic chemistry
• Written by authoritative experts who cover a wide range of topics that require a quantitative, molecular-level understanding of phenomena across a diverse range of disciplines