Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Applications
Comprehensive Analytical Chemistry Series

Language: English
Cover of the book Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Applications

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Keywords

Accurate mass; Bioanalytical; Chemoproteomics; Chiral mass spectrometry; Chiral stationary phase; Cold EI; Comprehensive two-dimensional liquid chromatography; CP-MIMS; DBPs; Direct mass spectrometry; Disinfection by-products; DMS; Drinking water; EI-LC-MS-SMB; Electron ionization; Emerging contaminants; Emerging DBPs; Enantioseparation; Environmental matrices; Environmental; FAIMS; Food products; Free concentration; Glycomics; High resolution mass spectrometry; High-performance liquid chromatography; HILIC (hydrophilic interaction liquid chromatography)HPAEC (high-pH anion-exchange chromatography)Ion mobility; Hydraulic fracturing fluids; Immunoassay; Intrinsic physical properties; Ion mobility; LC×LC-MS interfaces; LC-EI-MS; LC-MS in biomedical field; LC-MS/MS; LC-MS; Liquid chromatography; Liquid chromatography-mass spectrometry; Liquid-EI (LEI)Mass spectrometry; Mass spectrometry; Membrane introduction mass spectrometry; Membrane permeability; Metabolomics; MIMS; MS/MS; N-glycans; Online and real-time chemical measurement; Peptides and proteins; PGC (porous graphitized carbon)RP C18 (reversed-phase)Tandem MS; Pharmaceutical products; Pharmaceuticals; Pharmacokinetics; Phosphoproteomics; Phytoremediation; Proteomics; Quadrupole/time-of-flight mass spectrometry (QTOF-MS)UHPLC; Quantitative proteomics; Rapid screening; Reaction monitoring; Steroid hormones; Steroid profiling; Supersonic molecular beam (SMB)Tandem mass spectrometry; Targeted proteomics; TIMS; Trace analysis; T-wave; ultraFAIMS; Vitamin D; Xenobiotics

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Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Application, Volume 79, highlights the most recent LC-MS evolutions through a series of contributions by world renowned scientists that will lead the readers through the most recent innovations in the field and their possible applications.

Many authoritative books on LC-MS are already present in market, describing in detail the different interfaces and their principles of operation. This book focuses more on new trends, starting with the innovations of each technique, to the most progressive challenges of LC-MS.

1. Electron Ionization LC-MS: What is it and why use it? 2. Analysis of psychoactive substances, their metabolites and transformation products in environmental samples using LC-MS 3. New trends in chiral HPLC-MS4. Comprehensive techniques in LC-MS applications 5. Tools for Unknown identification: Accurate Mass Analysis of Hydraulic Fracturing fluids 6. Advanced LC-MS methods for N-glycan characterization 7. Condensed Phase Membrane Introduction Mass Spectrometry – Continuous, Direct and Online Measurements in Complex Samples8. Enhancing LC-MS biological analyses using differential mobility techniques (DMS and FAIMS)9. ESI and APCI LC-MS/MS in model investigations on the absorption and transformation of organic xenobiotics by poplar plants (Populus Alba) 10. LC-MS of Emerging Disinfection By-Products 11. The role of tandem mass spectrometry in clinical chemistry: quantification steroid hormone and Vitamin D 12. Some applications of LC-MS in the biomedical field: new analytical methodologies and instrument approaches 13. A step up LC-MS/MS for proteomics

  • Presents an understanding of the new advancements in LC and MS which are essential for a step forward in LC-MS applications
  • Provides insight into the state-of-the-art in the currently available LC-MS interfaces and their principle of use
  • Expounds on the new frontiers in LC-MS and their application potential