Reactive Intermediate Chemistry

Reactive Intermediate Chemistry presents a detailed and timely examination of key intermediates central to the mechanisms of numerous organic chemical transformations. Spectroscopy, kinetics, and computational studies are integrated in chapters dealing with the chemistry of carbocations, carbanions, radicals, radical ions, carbenes, nitrenes, arynes, nitrenium ions, diradicals, etc. Nanosecond, picosecond, and femtosecond kinetic realms are explored, and applications of current dynamics and electronic structure calculations are examined.

Reactive Intermediate Chemistry provides a deeper understanding of contemporary physical organic chemistry, and will assist chemists in the design of new reactions for the efficient synthesis of pharmaceuticals, fine chemicals, and agricultural products. Among its features, this authoritative volume is:

• Edited and authored by world-renowned leaders in physical organic chemistry.
• Ideal for use as a primary or supplemental graduate textbook for courses in mechanistic organic chemistry or physical chemistry.
• Enhanced by supplemental reading lists and summary overviews in each chapter.

Preface..

PART 1: REACTIVE INTERMEDIATES.

1. Carbocations (R.A. McClelland).

2. Crossing the Borderline Between SN1 and SN2 Nucleophilic Substitution at Aliphatic Carbon(T.L. Amyes, et al.).

3. Carbanions (S. Gronert).

4. Radicals (M. Newcomb).

5. Non-Kekul Molecules as Reactive Intermediates (J.A. Berson).

6. Organic Radical Ions (H.D. Roth).

7. Singlet Carbenes (M. Jones Jr. and R.A. Moss).

8. Stable Singlet Carbenes (G. Bertrand).

9. Triplet Carbenes (H. Tomioka).

10. Atomic Carbon (P.B. Shevlin).

11. Nitrenes (M.S. Platz).

12. Synthetic Carbene and Nitrene Chemistry (M.P. Doyle).

13. Nitrenium Ions (D.E. Falvey).

14. Silylenes (W. Ando and N. Tokitoh).

15. Strained Hydrocarbons: Structures, Stability, and Reactivity (K.B. Wiberg).

16. Arynes (M. Winkler, et al.).

PART 2: METHODS AND TEMPORAL REGIMES.

17. Matrix Isolation (T. Bally).

18. Nanosecond Laser Flash Photolysis: A Tool for Physica l Organic Chemistry (J.C. Scaiano).

19. The Picosecond Realm (E. Hilinski).

20. Reactions on the Femtosecond Time Scale (J.E. Baldwin).

21. Potential Energy Surfaces and Reaction Dynamics (B.K. Carpenter).

22. The Partnership Between Electronic Structure Calculations and Experiments in the Study of Reactive Intermediates (W.T. Borden).

Index.

Robert A. Moss is the Louis P. Hammett Professor of Chemistry at Rutgers, the State University of New Jersey, New Brunswick, NJ. He received his Ph. D. with Professor Gerhard Closs (Chicago) and was a postdoctoral student with Professor Ronald Breslow (Columbia). Dr. Moss has been an A.P. Sloan Foundation Fellow, and a visiting professor or scientist at M.I.T., the University of Oxford, the Politechnika (Warsaw), the Weizmann Institute, the National Research Council of Canada, and the Hebrew University of Jerusalem. He has more than 350 scientific publications in the areas of reactive intermediates and chemistry in molecular aggregates.

Matthew S. Platz was born in New York City and graduated from the State University of NY at Albany ( B.Sc. in Chemistry and Mathematics) in 1973 and obtained his Ph.D. in Chemistry studying with Professor Jerome Berson in 1976. After a postdoctoral stint with Professor Gerhard Closs, Platz joined the faculty of The Ohio State University in 1978 where he has spent his entire independent career. Platz served as chair of the OSU Chemistry Department from 1994-1999, was the Melvin S. Newman Professor (1994-2001), and was named Distinguished University Professor in 2001. Platz has been a Sloan Fellow, a Camille and Henry Dreyfus Teacher-Scholar, and a Cope Scholar of the American Chemical Society. He has over 200 scientific publications and holds over a dozen patents.

Maitland Jones, Jr. turned to chemistry only after the invention of the curveball by his peers made it clear that he would never be a major league centerfielder. He received his B.S. degree from Yale College and his M. S. and Ph. D. degrees from Yale University, where he studied with William von E. Doering. After a postdoctoral year with Jerry Berson at Wisconsin he came to Princeton in 1964 as an Instructor. He has been there ever since, and is now David B. Jones Professor of Chemistry. He has been a visiting professor at Columbia and Harvard