Description
Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C−H Bonds, 1st ed. 2016
Springer Theses Series
Author: McDonald Stacey L.
Language: EnglishSubjects for Copper-Catalyzed Electrophilic Amination of sp2 and sp3...:
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Add to cart the print on demand of McDonald Stacey L.Publication date: 04-2018
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Approximative price 105.49 €
In Print (Delivery period: 15 days).
Add to cart the print on demand of McDonald Stacey L.Publication date: 08-2016
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Description
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This thesis reports the latest developments in the direct amination of various C?H bonds using an H?Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines.
The material outlined in this book shows how McDonald achieved C?H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source.
McDonald?s findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.
Nominated as an outstanding PhD thesis by Duke University
Provides a comprehensive review of electrophilic aminations using O-benzoylhydroxylamines
Presents results which are relevant for medicinal chemistry, drug discovery and materials science
Includes supplementary material: sn.pub/extras
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