Description
Recent Trends in Carbohydrate Chemistry
Synthesis, Structure and Function of Carbohydrates
Coordinators: Rauter Amélia Pilar, Christensen Bjørn E., Somsák László, Kosma Paul, Adamo Roberto
Language: EnglishSubject for Recent Trends in Carbohydrate Chemistry:
Keywords
Amylose; Carbamate; Cellulose; Chemical synthesis; Chiral stationary phase; Conformation; Cyclic amylose; D-Enzyme; Double helix formation; Enantioseparation; Films; Gel; Glycophostones; Glycosyl boranophosphates; Glycosyl thiophosphates; Imino sugar-1-phosphonates; Inclusion complex formation; Linear amylose; Liquid chromatography; Order-disorder conformation; P-/C-glycosyl phosphonates; Phosphorylase; Polycondensation; Polysaccharides; Ring-opening polymerization; S-/O-glycosyl thiophosphonates; Separation; Silica; Solution properties; Sugar phosphonates; Supercritical fluid chromatography; Well-defined polymers; Xanthan
492 p. · 15x22.8 cm · Paperback
Description
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Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties.
Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry
I. Monosaccharide chemistry toward molecular diversity--Recent findings 1. Perspective on the transformation of carbohydrates under green and sustainable reaction conditions 2. Hydroxymethylfurfural (HMF) and Glucosyloxymethylfurfural (GMF) in Multi-Component Reactions 3. Alkynedicobalt complexes in carbohydrates: Synthetic applications 4. Molecular Diversity Through Gold-catalysis on Saccharide Building Blocks 5. Glycomimetics with unnatural glycosidic linkages 6. Synthetic Approaches to Functionalized Oxepanes and Azapanes from Monosaccharides 7. N- and C-Glycopyranosyl Heterocycles as Glycogen Phosphorylase Inhibitors 8. Recent developments in synthetic methods for sugar phosphates, phosphonates and analogous P-containing compounds
II. Structure-function relationships in polysaccharides 16. Polysaccharides: chemical synthesis 17. Linear and cyclic amylose, beyond natural 18. Modification of xanthan in the ordered and disordered states 19. Derivatized polysaccharides on silica and hybridized with silica in chromatography and separation – a mini review
Synthetic organic chemists as well as conjugation and protein chemists, immunologists, and microbiologists in academia as well as industry
Bjørn E. Christensen holds a Dr. philos. degree in biotechnology from NTNU - Norwegian University of Science and Technology, Norway, where he also had a career as research scientist until 2002 when he became a full professor. His research field is polysaccharide engineering and includes studies of macromolecular characterisation and structure-function relationships in among other alginates, chitosans, pectins, xanthan and ß-1,3-glucans. He has also been visiting scientist/professor at Montana State University, USA (1985), Osaka Prefecture University, Japan (2009), Cermav-CNRS Grenoble, France (2010) and University of Bordeaux, France (2016).
Full professor, former director of the Institute of Chemistry and head of the Department of Organic Chemistry of the University of Debrecen, Hungary. Serves as an editorial board member for Carbohydrate Research, and as guest editor for special issues of Carbohydrate Research, Mini-Reviews in Medicinal Chemsitry, Molecules, Topics in Heterocyclic Chemistry. Research interests include synthetic carbohydrate chemistry directed to C-glycosyl compounds, anomeric-spirocycles, glycals, exo-glycals and their derivat
- Demonstrates the importance of carbohydrate chemistry as green and sustainable chemistry
- Details monosaccharide syntheses and transformations toward biologically active small molecular entities
- Provides the most recent findings on polysaccharide synthesis and bioapplications
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