Cell-Based Microarrays, 2014
Review of Applications, Developments and Technological Advances
SpringerBriefs in Cell Biology Series

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Language: English

52.74 €

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100 p. · 15.5x23.5 cm · Paperback
This book is a review on the evolution of cell-based microarrays and an update to the author's earlier book Methods in Molecular Biology: Cell-Based Microarrays. Since their development in 2001, cell-based microarrays have advanced signi?cantly to include expression arrays, short interfering RNA arrays and antibody arrays. The surface used to coat the glass slides has also been significantly improved to allow non-adherent cells to bind to the arrays.
1 Cell-based microarrays: recent advances for gene function analyses.- 2 Review of siRNA/shRNA Applications in Cell-Based Microarrays.- 3 Antibody microarrays for cell-based assays: The use of micro-arrayed antibodies for exploring cell surface diversity or whole cell functionality.- 4 Polymer microarrays for high throughput biomaterials discovery.- 5 Microfluidics cell-based microarray review.

Ella Palmer is a molecular biology expert. She undertook her Ph.D. at the University of Cambridge, where she developed a large-scale cell-based microarray and identified potential new genes involved in apoptosis, for which a patent was registered. She has since held postdoctoral positions at Imperial College in London, examining the cell polarity of Drosophila photoreceptors, and at University College London, working on a quantitative systems biology initiative for single cell analysis of the NFAT pathway. Most recently she has been working as an intern at a medical writing company.

Explores the evolution of cell-based microarrays Reviews and updates four key aspects of cell-based microarrays Updates the earlier work Methods in Molecular Biology: Cell-Based Microarrays