Microfluidics in Cell Biology: Part A: Microfluidics for Multicellular Systems

Language: English

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273 p. · 19x23.3 cm · Hardback

Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids, Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chip for pharmacokinetic analysis, Cancer immunotherapy on chips, and more.

Section 1: Microfluidics for Cell Monolayers/Spheroids 1. Tubular microscaffolds for studying collective cell migration Wang Xi, Surabhi Sonam, Chwee Teck Lim and Benoit Ladoux 2. Endothelial cell monolayer-based microfluidic systems mimicking complex in vivo microenvironments for the study of leukocyte dynamics in inflamed blood vessels Jaehyun Lee, Hyung Kyu Huh, Sung Ho Park, Sang Joon Lee and Junsang Doh 3. Constrained spheroids/organoids in perfusion culture Fan Lee, Ciprian Iliescu, Fang Yu and Hanry Yu

Section 2: Organs on Chips 4. Generation of functional cardiac microtissues in a beating heart-on-a-chip Giovanni Stefano Ugolini, Roberta Visone, Daniela Cruz-Moreira, Andrea Mainardi and Marco Rasponi 5. Kidney on chips Jeonghwan Lee, Kipyo Kim and Sejoong Kim 6. Liver sinusoid on a chip Yu Du, Ning Li and Mian Long 7. Pathomimetic modeling of human intestinal diseases and underlying host-gut microbiome interactions in a gut-on-a-chip Woojung Shin and Hyun Jung Kim 8. 3D in vitro microvascular model-based lymphoma model Robert G. Mannino, Pallab Pradhan, Krishnendu Roy and Wilbur A. Lam 9. Blood–brain barrier on a chip Eyleen Goh 10. Pharmacokinetic-based multi-organ chip for recapitulating organ interactions Jong Hwan Sung 11. Studying TCR T cell anti-tumor activity in a microfluidic intrahepatic tumor model Giulia Adriani, Andrea Pavesi and Roger D. Kamm

Section 3: Microfluidics for Model Organisms 12. Microfluidics for mechanobiology of model organisms Anna A. Kim, Adam L. Nekimken, Sylvia Fechner, Lucy E. O'Brien and Beth L. Pruitt

  • Contains contributions from experts in the field from across the globe
  • Covers a wide array of topics on both mitosis and meiosis
  • Includes relevant, analysis based topics