Principles & methods of toxicology (5^th Ed.)

Now in its fifth edition, this core text and standard reference in toxicology brings together more than 70 distinguished investigators to detail testing procedures, offer guidelines on data interpretation and highlight major areas of controversy. The book deals with the methods of toxicology, as well as principles and agents, allowing the working toxicologist, whether a senior professional or graduate student, to understand and use basic experiments in toxicology. It includes chapters on exposure assessment and epidemiology for toxicologists.

The Art, the Science, and the Seduction of Toxicology: An Evolutionary Development. The Use of Toxicology in the Regulatory Process. Metabolism: A Determinant of Toxicity. Toxicokinetics: Pharmacokinetics in Toxicology. Physiologically Based Pharmacokinetic Modeling in Toxicology. The Toxicological Assessment of Pharmaceutical and Biotechnology Products. Statistics for Toxicologists. Quantitative Extrapolations in Toxicology. The Practice of Exposure Assessment. Epidemiology for Toxicologists. Food-Borne Toxicants. Solvents and Industrial Hygiene. Crop Protection Chemicals. Metals. Ionizing Radiation. The Use of Laboratory Animals in Toxicologic Research. Genetic Toxicology. Acute Toxicity and Eye Irritancy. Short-Term, Subchronic and Chronic Toxicology Studies. Principles of Testing for Carcinogenic Activity. Principles of Clinical Pathology for Toxicology Studies. Dermatotoxicology. Inhalation Toxicology. Detection and Evaluation of Chemically Induced Liver Injury. Renal Methods for Toxicology. Methods in Gastrointestinal Toxicology. Cardiovascular Physiology and Methods for Toxicology. Assessment of Male Reproductive Toxicity. Test Methods for Assessing Female Reproductive and Developmental Toxicology. Hormone Assays and Endocrine Function. Immunotoxicology: Effects of, and Response to, Drugs and Chemicals. Assessment of Behavioral Toxicity. Application of Isolated Organ Perfusion Techniques in Toxicology. Organelles as Tools in Toxicology. Analysis and Characterization of Enzymes and Nucleic Acids. Modern Instrumental Methods for Studying Mechanisms of Toxicology. Methods in Environmental Toxicology.