Description
Synthetic biology
A primer
Authors: FREEMONT Paul S., KITNEY Richard I.
Language: EnglishSubjects for Synthetic biology:
Approximative price 49.28 €
In Print (Delivery period: 15 days).
Add to cart the book of FREEMONT Paul S., KITNEY Richard I.
Publication date: 09-2012
250 p. · Paperback
250 p. · Paperback
Description
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"Synthetic Biology - A Primer" gives a broad overview of the emerging
field of synthetic biology and the foundational concepts on which it is
built. It will be of interest to final year undergraduates, postgraduates
and established researchers who are interested in learning about this
exciting new field. The book introduces readers to fundamental concepts in
molecular biology and engineering and then explores the two major themes
for synthetic biology, namely 'bottom-up' and 'top-down' engineering
approaches. 'Top-down' engineering utilises a conceptual framework of
engineering and systematic design to build new biological systems by
integrating robustly characterised biological parts into an existing
system through the use of extensive mathematical modelling. The
'bottom-up' approach involves the design and building of synthetic
protocells using basic chemical and biochemical building blocks from
scratch. Exemplars of cutting-edge applications designed using synthetic
biology principles are presented, including the production of novel
biofuels from renewable feedstocks, microbial synthesis of pharmaceuticals
and fine chemicals, and the design and implementation of biosensors to
detect infections and environmental waste. The book also uses the
Internationally Genetically Engineered Machine (iGEM) competition to
illustrate the power of synthetic biology as an innovative research and
training science. Finally, the primer includes a chapter on the ethical,
legal and societal issues surrounding synthetic biology, illustrating the
integration of social sciences in synthetic biology research.
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