The Inner Workings of Life
Vignettes in Systems Biology

Living systems are dynamic and extremely complex and their behaviour is often hard to predict by studying their individual parts. Systems biology promises to reveal and analyse these highly connected, regulated and adaptable systems, using mathematical modelling and computational analysis. This new systems approach is already having a broad impact on biological research and has potentially far-reaching implications for our understanding of life. Written in an informal and non-technical style, this book provides an accessible introduction to systems biology. Self-contained vignettes each convey a key theme and are intended to enlighten, provoke and interest readers of different academic disciplines, but also to offer new insight to those working in the field. Using a minimum amount of jargon and no mathematics, Voit manages to convey complex ideas and give the reader a genuine sense of the excitement that systems biology brings with it, as well as the current challenges and opportunities.

Appetizer; Acknowledgements; 1. Status: it's complicated; 2. I'd rather be fishin'; 3. Whizzes and apparitions; 4. Why?; 5. Simply engenious!; 6. Just a little bit; 7. Supermodels; 8. Close only counts in horseshoes and hand grenades; 9. Emergence preparedness; 10. Life without chaos?; 11. What God hath wrought!; 12. Tell me with whom you go and I'll tell you who you are; 13. Time for a change; 14. Can't we all get along?; 15. Love thyself and fight all others; 16. A billion dollars for your thoughts!; 17. The computer will see you now; 18. Redesigning perfect; 19. Let me go in the agorá!; 20. Dessert; Selected further readings and citations; Gentle jargon; Index.

Eberhard Voit is a pioneer and leader in systems biology with a passion for education at all levels. He is Professor and David D. Flanagan Chair in Biological Systems, as well as a Georgia Research Alliance Eminent Scholar in the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University. He is the author of one of the leading textbooks in the field, wrote one of the first systems biology books to be published, and has written over 250 scientific articles. His research focuses on genomic, metabolic, and signalling systems with applications reaching from microbial, ecological, and plant systems to human diseases.