Description
Cushing's Disease
An Often Misdiagnosed and Not So Rare Disorder
Coordinators: Laws Jr Edward R., Pace Louise
Language: English
Subject for Cushing's Disease:
Keywords
adenoma; adrenal gland; adrenal insufficiency; adrenalectomy; adrenocorticotropic hormone; aryl-hydrocarbon receptor interacting protein (AIP); cabergoline; Centers of Excellence; clinical features; cognitive function; comorbidities; coping strategies; corticotropin-releasing hormone; cortisol; Crooke's cell; Cushing's disease; Cushing's syndrome; cyclin-dependent kinase inhibitor; delayed diagnosis; depression; deubiquitinase (USP8) gene; diabetes insipidus; ectopic adrenocorticotropic hormone secretion; endocrinology; endoscopic surgery; epidemiology; feedback loop; genetic targets; glucocorticoid receptor; growth hormone; hippocampal atrophy; homeostasis; hypercortisolism; hypophysectomy; hypopituitarism; hypothalamus; imaging diagnosis; incidence; inferior petrosal sinus sampling; ketoconazole; levoketoconazole; MALDI mass spectrometry; medical therapy; memory; metabolic imaging; metyrapone; mifepristone; mortality; multidisciplinary care; multiple endocrine neoplasia; Nelson's syndrome; neurosurgery; osilodrostat; pasireotide; patients' perspectives; pediatric Cushing's syndrome; pituitary adenoma; pituitary gland; prevalence; prolactin; quality of life; radiation oncology; radiosurgery; reproductive system; thyroid gland; transsphenoidal surgery; ventromedial prefrontal cortex
Support: Print on demand
Description
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Cushing?s Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing?s, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility.
Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient?s perspective, coping with Cushing?s, quality of life, and psychosomatic issues.
This book is essential reading for the wide range of physicians who treat patients with Cushing?s disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders.
1. The Pituitary Gland: Anatomy, Physiology, and its Function 2. Epidemiology and Etiology of Cushing’s Disease 3. Physical Presentation of Cushing’s Syndrome: Typical and Atypical Presentations 4. The Cognitive, Psychological, and Emotional Presentation of Cushing’s Disease 5. Making the Diagnosis: Laboratory Testing and Imaging Studies 6. Surgical Treatment of Cushing’s Disease 7. Medical Treatment of Cushing’s Disease 8. Multidisciplinary Management of Cushing’s Disease: Centers of Excellence Approach 9. Posttreatment Management of Cushing’s Disease 10. Coping with Cushing’s Disease: the Patients’ Perspectives 11. Cushing’s Disease in Children and Adolescents: Diagnosis and Management 12. Challenges and Future Developments for Improvement in the Diagnosis and Management of Cushing’s Disease Appendix. Patients’ Perspectives
Founder and President, Cushing's Support and Research Foundation
- Reviews the basics of Cushing’s disease and its interrelation with hormones, the brain, and bodily functions
- Includes chapters on diagnosis, surgical, medical, and radiotherapeutic treatments, and variations in presentation, including cyclical disease
- Presents the cognitive and emotional aspects of Cushing’s and the long-term sequelae
- Offers an important resource for physicians who are accustomed to treating individual symptoms rather than a disease complex
- Reviews multidisciplinary management, and post-treatment management of Cushing’s, including recommendations for Cushing’s Centers of Excellence
