Layer-by-Layer Films for Biomedical Applications

PART I. CONTROL OF CELL/FILM INTERACTIONS. Controlling Cell Adhesion Using pH-Modified PEM Films. Carbon Nanotube-Based Antimicrobial Coatings. Ion Diffusion and Permeability of PEM Films. Directing Stem Cell Differentiation. Drug Release from Hydrogels and LbL Films. Cell Response to Film Stiffness. Bioactive and Spatially Organized LbL Films. PART II. DELIVERY OF SMALL DRUGS, ANTIBACTERIALS AGENTS AND DNA. Antimicrobial LbL Films. Releasable LbL Assemblies for Targeted Applications. LbL Polyelelectrolyte Nanocoating. LbL Microcapsules Based on Functional Polysaccharides. Release of Functional Plasmid DNA Using LbL Films. Gene Delivery Using LbL Films. PART III. NANO- AND MICROCAPSULES AS DRUG CARRIERS. Designing LbL Capsules for Drug Loading and Release. Chemosensors and Biosensors Based on LbL Microcapsules. Light Addressable Microcapsules. Nanoparticle-Functionalized Surfaces. Nanoengineered Capsules: Moving into the Biological Realm. Mutlifunctional Cytotoxic Stealth Particles. Layer-by-Layer Nanoshells for Direct Regulation of Cell Activity. Drug Nanocapsules. Red Blood Cell Coating. Biocompatible and Biogenic Microcapsules. PART IV. ENGINEERED TISSUES AND COATINGS OF IMPLANTS. Toward Cellularized Blood Vessels. Tracheal Prosthesis. Biomimetic Surface Engineering of Nanoparticles. Vascular Coatings. Neural Prosthetic Devices. 3D Engineered Tissues Using LbL Assembly. Musculo-Skeletal Tissue Engineering. Regulation of Stem Cell Differentiation. Hepatocyte Tissue Engineering Using LbL Assembly.

Catherine Picart is full Professor of Bioengineering and Biomaterials at the Grenoble Institute of Technology, France, and former junior member of the Institut Universitaire de France (2006-2011). She obtained her PhD in Biomedical Engineering from the University Joseph Fourier, Grenoble, and did post-doctoral research at the University of Pennsylvania, USA. Afterwards she joined the University Louis Pasteur, Strasbourg, as Assistant Professor and later the Department of Biology and Health at the University of Montpellier 2 as Associate Professor. Catherine Picart's research focuses on the assembly of biopolymers, protein/lipid interactions, and musculo-skeletal tissue engineering. She has authored more than 90 original articles and 6 reviews in international peer-reviewed journals. She received two ERC Grants from the European Research Council: a starting grant at the consolidator stage in 2010 and a Proof of Concept in 2012 to further develop osteoinductive layer-by-layer films for orthopedic and dental clinical applications. In 2013, she was nominated "Chevalier de l'ordre National du Merite" by the French Ministry of Research

Frank Caruso is a Professor in the Department of Chemical and Biomolecular Engineering at the University of Melbourne, Australia. He was awarded an Australian Research Council Laureate Fellowship 2012 for recognition of his significant leadership and mentoring role in building Australia's internationally competitive research capacity. He has published over 350 peer-reviewed papers and is on ISI's most highly cited list, ranking in the top 20 worldwide in materials science in 2011. Frank Caruso is also included in Thomson Reuters' 2014 World's Most influential scientific minds. He was elected a Fellow of the Australian Academy of Science in 2009. Prof. Caruso is also the recipient of the inaugural 2012 ACS Nano Lectureship Award (Asia/Pacific) from the American Chemical Society for global impact in nanoscience and nanotechnology, t