Pathogenesis of Periodontal Diseases, Softcover reprint of the original 1st ed. 2018
Biological Concepts for Clinicians

Coordinators: Bostanci Nagihan, Belibasakis Georgios N.

Language: English
Cover of the book Pathogenesis of Periodontal Diseases

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Pathogenesis of Periodontal Diseases
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Approximative price 137.14 €

In Print (Delivery period: 15 days).

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Pathogenesis of Periodontal Diseases
Publication date:
Support: Print on demand

This book aims to provide clinicians with a refined understanding of the biology that underlies periodontal diseases, thereby offering a sound basis for improved clinical decision making with regard to prevention strategies, diagnosis, and therapy. All significant aspects of periodontal pathogenesis are covered, including the roles played by the oral microbiome and biofilms, bacterial virulence factors, cells of the immune system, matrix metalloproteinases, proinflammatory and osteolytic cytokines, genetic factors, and antimicrobial peptides.

Periodontal diseases are among the most common infectious diseases in humans, and the primary cause of tooth loss in adults. The functional and esthetic problems associated with these diseases compromise quality of life, and their treatment imposes large financial burdens on national health systems and private patients. Up-to-date knowledge of periodontal pathogenesis is therefore essential for the contemporary clinician. This book, written by experts from Europe and the Americas, delivers such knowledge in an accessible, clinician-friendly way.

Periodontal Pathogenesis: Introduction and Definitions.- Diversity of the Oral Microbiome in Periodontal Health and Disease.- Subgingival Biofilms as Etiological Factors of Periodontal Diseases.- Bacterial Virulence Factors that Contribute to Periodontal Pathogenesis.- Central Role of Neutrophils in Periodontal Pathogenesis.- Active Matrix Metalloproteinase 8 - Contributor to Periodontitis and a Missing Link between Dentistry and Medicine.- Inflammatory Pathways of Bone Resorption in Periodontitis.- Genetic Influences on the Periodontal Microbial-Host Cross-Talk.- Antimicrobial Peptides: Roles in Periodontal Health and Disease.- Periodontal Pathogenesis: Conclusions and Future Directions.

Prof. Bostanci is dually qualified with a Dental degree (Ege University, Izmir, Turkey, 1999) and a PhD in Periodontology (University of London, UK, 2007). She also received advanced clinical training in Periodontology (Ege University, Izmir and Eastman Dental Institute, London). In 2007-2008, she worked as Clinical Lecturer at the Centre for Clinical and Diagnostic Oral Sciences, Barts and the London Dental Institute, QMUL. In 2008-2009 she attained a Walport Clinical Academic Lectureship funded by the National Institute of Health Research (NIHR), at the Division of Periodontology, UCL Eastman Dental Institute, London, UK. From 2009 until 2016 she was Principal Investigator at the Institute of Oral Biology, Center of Dental Medicine of the University of Zürich, Switzerland. In 2013 she attained her Habilitation (Venia Legendi) in Oral Biology and Periodontology. She has received distinguished scientific awards in her field, including the Sir Wilfred Fish Price of the British Society of Periodontology, the Philips Oral Healthcare Young Investigator Research Prize and the Sigmund Socransky Young Investigator Award of the International Association for Dental Research (IADR). She is Associate Editor for BMC Oral Health and Editorial Board member for Oral Health and Preventive Dentistry, and Frontiers of Cellular and Infection Microbiology. Her work is a great example of incorporation of basic sciences into clinical research, focusing on the investigation of various molecular biomarkers of disease in biological samples (including oral tissue, gingival crevicular fluid, serum and saliva). Hence, her special research interests span from diagnostic and prognostic molecular markers for periodontal diseases, to the impact of oral health on general health. She is currently Professor of Inflammation Research specializing in Periodontics, at the Department of Dental Medicine, Karolinska Institute, Sweden.

Prof. Belibasakis studied Dentistry

Presents the latest knowledge on periodontal pathogenesis in a clinician-friendly way

Explains the roles played by a wide range of factors

Provides a sound basis for improved clinical decision making