Handbook of Immunoassay Technologies (2nd Ed.)
Approaches, Performances, and Applications

Coordinators: Vashist Sandeep K., Luong John H.T.

Language: English

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600 p. · 15x22.8 cm · Paperback
Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from conventional enzyme-linked immunosorbent assays to smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays and are all discussed in this comprehensive text. Revised and updated, the Second Edition of the Handbook of Immunoassay Technologies covers all the relevant, timely, and important future developments in this field. This edition offers new content on topics such as: antibody production for immunodiagnostics; mass spectroscopy-based immunoassays; multiplex immunoassays; Luminex xMAP technology-based immunoassays; immunoassays for newborn screening; biotin interference in immune-assays and strategies to tackle it; strategies for the prolonged stability of immunoreagents; bioanalytical tools for characterizing immunoreagents; and harmonization of immunoassays. The addition of these new topics makes the Second Edition a valuable, up-to-date, and comprehensive resource on immunoassays.
1. Immunoassays: An Overview
2. Antibody Immobilization and Surface Functionalization Chemistries for Immunodiagnostics
3. Antibody production for immunodiagnostics
4. Monoclonal Antibody Generation by Phage Display: History, State-of-the-art, and Future
5. Bioanalytical Requirements and Regulatory Guidelines for Immunoassays
6. Enzyme-linked Immunoassays
7. Chemiluminescent immunoassays
8. Surface Plasmon Resonance-based Immunoassays: Approaches, Performance and Applications
9. Lateral Flow Immunoassays
10. Paper-based Immunoassays
11. Acoustic Wave based Immunoassays
12. Interferometry based Immunoassays
13. Nano- and Micro-Materials based Immunoassays
14. Microcantilever-based sensors
15. Quartz crystal microbalance-based sensors
16. Electrochemical Immunosensors: Fundamentals and Applications of Clinical Diagnostics
17. Mass spectroscopy-based Immunoassays
18. (Sandeep K. Vashist and co-workers)
19. Lab-on-a-Chip Immunoassays
20. Smartphone-based Immunoassays
21. Multiplex immunoassays
22. Immunoassays for newborn screening
23. Biotin interference in immunoassays and strategies to tackle it
24. Strategies for prolonged stability of immunoreagents
25. Bioanalytical tools for characterizing immunoreagents
26. Harmonization of immunoassays
27. In Vitro Diagnostic immunoassays for SARS-CoV-2
28. Immunoassays for deadly viruses: Ebola and HIV
29. Immunoassays: Future Prospects, and Possibilities
Dr. Sandeep K. Vashist is the Senior Discovery and R&D Processes Manager at Immunodiagnostic Systems GmbH, Germany. He worked as the Bioanalytical Scientist at Bristol-Myers Squibb Ireland; Team Leader for point-of-care (POC) diabetic monitoring at National University of Singapore; Head of Immunodiagnostics at Hahn-Schickard, Germany; Senior Scientist in immunoassays and POC testing at Klinikum rechts der Isar der Technischen Universität München, Germany; Chief Scientific Officer at Vallomed Health Care GmbH, Germany; and, Founder and Director of Vallomed Smart Health Solutions. His research outputs include many successful technology transfers; several immunoassays, IVD and POC technologies; over 250 high impact factor journal publications, conference publications, patents, books, and book chapters. He has been constantly rewarded for scientific research excellence and innovation. Further, he is the invited Editor for many reputed journals; an expert/reviewer/advisor for several international funding agencies; and, a Technology consultant to several companies in the fields of immunoassays, in vitro diagnostics, POC technologies, mobile healthcare, bioanalytical sciences, and diabetic monitoring and management.
Prof John H.T. Luong is the Walton Fellow and Professor associated with the School of Chemistry of University College Cork, Ireland. He was the Professor and Division Head of Biomedical Engineering of Nanyang Technological University, Singapore. He was also a distinguished Visiting Professor at University of Zhengzhou (China), a Visiting Professor at Nanocore, National University of Singapore, Bar-Ilan University (Ramat Gan-Israel), and Institut d'Electronique, de Microélectronique et de Nanotechnologie, Université de Lille. He has received several awards for his excellent contribution in research, innovation and technology transfer. He is on the Editorial Board of several Journals and the Chief Editor of Frontiers in Biotechnology and Bioengineering- Nano
  • Provides comprehensive details of various types of immunoassays utilized in healthcare as well as industrial, environmental, and other biochemical settings
  • Offers extensive knowledge and guided insights on multifarious aspects of immunoassays and types of immunoassays developed to date
  • Comprehensively describes immunoassay formats along with their principles of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications
  • Provides increased technical know-how as it is written by renowned experts and key opinion makers in the field of immunoassays with decades of experience