Vascular Pharmacology: Cytoskeleton and Extracellular Matrix

Vascular Pharmacology: Cytoskeleton and Extracellular Matrix, Volume 81, contains the latest information on the vascular cytoskeleton and extracellular matrix that is presented with helpful illustrations and supporting references by prominent scientists and highly-recognized experts in the vascular field. Topics of interest in this new release include Pharmacology of the Vascular Cytoskeleton and Extracellular Matrix, The Dynamic Actin Cytoskeleton in Smooth Muscle, The Role of the Actin Cytoskeleton in the Regulation of Vascular Inflammation, The Smoothelin Family of Proteins and the Smooth Muscle Cell Contractile Apparatus, Smooth Muscle Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF, and more.

1. The Dynamic Actin Cytoskeleton in Smooth Muscle Dale D. Tang 2. Smoothelins and the Control of Muscle Contractility Megha Murali and Justin A. MacDonald 3. The Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF in Vascular Smooth Muscle Cells Rohan Samarakoon and Paul J. Higgins 4. Basic Components of Vascular Connective Tissue and Extracellular Matrix Jaroslava Halper 5. Integrins in Vascular Development and Pathology Paola A. Guerrero and Joseph H. McCarty 6. Mechanotransduction in Blood and Lymphatic Vascular Development and Disease Sofia Urner, Molly Kelly-Goss, Shayn M. Peirce and Eckhard Lammert 7. Extracellular Matrix Macromolecules as Potential Targets of Cardiovascular Pharmacotherapy Annele Sainio and Hannu Järveläinen 8. Matrix Metalloproteinases, Vascular Remodeling, and Vascular Disease Xi Wang and Raouf A. Khalil 9. Mechanisms of I/R-Induced Endothelium-Dependent Vasodilator Dysfunction Ronald J. Korthuis 10. The Role of Age-Related Intimal Remodeling and Stiffening in Atherosclerosis Jacob A. VanderBurgh and Cynthia A. Reinhart-King

This volume of Advances in Pharmacology focuses on the vascular cytoskeleton and extracellular matrix and their role under both physiological and pathological conditions. Intended audience is undergraduate and graduate students and postgraduate trainees as well as established scientists, physicians and medical professionals with interest in the vascular field.

• Presents a must-read book on the vascular cytoskeleton and extracellular matrix
• Contains up-to-date information on the structure, function and development of the vascular cell cytoskeleton
• Includes contributors from prominent scientists and highly-recognized experts with major accomplishments in the fields of the vascular cytoskeleton, extracellular matrix, mechanotransduction and vascular remodeling