Advances in Immunology
Advances in Immunology Series

Coordinator: Alt Frederick W.

Language: English

Subject for Advances in Immunology

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248 p. · 15x22.8 cm · Hardback
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
      1. Classical and Alternative End Joining Pathways for Repair of Lymphocyte-Specific and General DNA Double-Strand Breaks
      2. Cristian Boboila, Frederick W. Alt and Bjoern Schwer

      3. The Leukotrienes Immune Modulating Lipid Mediators of Disease
      4. Antonio Di Gennaro and Jesper Z. Haeggström

      5. Gut Microbiota Drives Metabolic Diseases in Immunologically Altered Mice
      6. Benoit Chassaing, Jesse D Aitken, Andrew T Gewirtz and Matam Vijay-Kumar

      7. What is Unique about the IgE Response?
      8. Huizhong Xiong, Maria A. Curotto de Lafaille and Juan J. Lafaille

      9. Prostanoids as Regulators of Innate and Adaptive Immunity
      10. Takako Hirata and Shuh Narumiya

      11. Lymphocyte Developmental: Integration of DNA Damage Response Signaling

      Jeffrey J. Bednarski and Barry P. Sleckman

Immunologists and infectious disease specialists, cell biologists and hematologists
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field