Advances in Immunology
Advances in Immunology Series, Vol. 92

Coordinator: Alt Frederick W.

Language: Anglais
Cover of the book Advances in Immunology

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344 p. · 15.2x22.9 cm · Hardback
Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Systemic Lupus Erythematosus; Genetics of man and mouse
Avian models with spontaneous autoimmune diseases
Functional dynamics of naturally-occurring regulatory T cells in health and autoimmunity
BTLA and HVEM Cross-Talk Regulates Inhibition and Costimulation
The human T cell response to melanoma antigens
Virus and Protein Quality Control: Implications for Antigen Processing and Presentation
Immunologists and infectious disease specialists, cell biologists and hematologists
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.