Description
Biophysics for Therapeutic Protein Development, 2013
Biophysics for the Life Sciences Series, Vol. 4
Coordinator: Narhi Linda O.
Language: EnglishSubjects for Biophysics for Therapeutic Protein Development:
Publication date: 03-2015
Support: Print on demand
Publication date: 02-2013
293 p. · 15.5x23.5 cm · Paperback
Description
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This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where the focus is on identifying targets, and screening for potential drug product candidates, through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, and commercial support including investigations.
Organized to mimic biotherapeutic product lifecycle
Focuses on the applications of biophysics to different disciplines; in particular, focusing on protein therapeutic development
First fully comprehensive book to cover protein aggregation and the biophysical techniques used in the development lifecycle of biopharmaceuticals
Includes supplementary material: sn.pub/extras