Cancer Clinical Pharmacology

Cancer Clinical Pharmacology provides a comprehensive account of the scientific basis of anti-cancer therapy in patients with solid tumours and haematological malignancies. An international group of experts have brought together information on the basic principles of pharmacology and tumour biology, bioanalytical aspects, pharmacokinetics, and the pharmacodynamics of anti-cancer agents. The clinical pharmacology of individual anti-cancer agents are covered, including the most important recently registered novel anti-cancer drugs. This book will prove an invaluable source of information for all trainees in oncology, haematology and internal medicine. Since cancer clinical pharmacology is a vast subject this book will be useful for all individuals involved in cancer pharmacology such as nurses, pharmacists, general pharmacologists, and cancer scientists.

1: Jos H Beijnen & Hilde Rosing: Bio-Analytical Methods for Anticancer Drugs, 2: Etienne Chatelut: Principles of Pharmacokinetics, 3: Jan H M Schellens: Clinical Implications and Mechanisms of Variability in the Response to Anticancer Agents, 4: Jim Cassidy: Drug Development and Study Design, 5: Gerard Milano & Jan H M Schellens: Pyrimidine Antimetabolites, 6: Jan Liliemark & Curt Peterson: Purine Analogs and Antifolates, 7: Alan. Part 5: Boddy. Alkylating Agents, 8: Howard L McLeod: Epipodophyllotoxins, 9: Jacques Robert: Anthracyclines, 10: Lucia Vigano, Alberta Locatelli & Luca Gianni: Taxanes, 11: Timothy W Synold: Vinca Alkaloids, 12: Eric K Rowinsky & Sharyn D Baker: Topoisomerase I-Targeting Agents, 13: Steven W Johnson, James P Stevenson & Peter J O'Dwyer: Platinum Agents, 14: Wandena S Lakhai, Jos H Beijnen & Jan H M Schellens: Novel Tyrosine Kinase Inhibitors: Focus on Imatinib and Gefitinib, 15: Per E Lonning: Antiendoctrine Drugs used in Cancer Treatment, 16: D Paul Harkin & Patrick G Johnston: The Clinical Application of Tumor Biology