Description
Endogenous ADP-Ribosylation, Softcover reprint of the original 1st ed. 2015
Current Topics in Microbiology and Immunology Series, Vol. 384
Coordinator: Koch-Nolte Friedrich
Language: EnglishSubjects for Endogenous ADP-Ribosylation:
Publication date: 08-2016
Support: Print on demand
Publication date: 11-2014
213 p. · 15.5x23.5 cm · Hardback
Description
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This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections:
· Evolution and detection of endogenous ADP-ribosylation
· ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs)
· ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs)
The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.
Part I: Evolution and Detection of Endogenous ADP-Ribosylation
The natural history of ADP-ribosyltransferases and the ADP ribosylation system
L. Aravind, Dapeng Zhang, Robson F. de Souza, Swadha Anand and Lakshminarayan M. Iyer
Identification and Analysis of ADP-ribosylated Proteins
Friedrich Haag and Friedrich Buck
Part II: ADP-Ribosylation by ARTCs (R-S-E ARTs)
Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine
Klaus Aktories, Gudula Schmidt and Alexander E. Lang
Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein
Hideaki Tsuge, Toshiharu Tsurumura
Regulation of nitrogenase by reversible mono-ADP-ribosylation
Vivian R. Moure, Flavia F. Costa, Leonardo M. Cruz, Fabio O. Pedrosa, Emanuel M. Souza, Xiao-Dan Li, Fritz Winkler and Luciano F. Huergo
ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells
Björn Rissiek, Friedrich Haag, Olivier Boyer, Friedrich Koch-Nolte, Sahil Adriouch
Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish
Tsuyoshi Nakano, Azusa Takahashi-Nakaguchi, Masafumi Yamamoto, and Masahiko Watanabe
Part III: ADP-Ribosylation by ARTDs (H-Y-E ARTs)
Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family
Ana Filipa Pinto and Herwig Schüler
Function and regulation of the mono-ADP-ribosyltransferase ARTD10
Max Kaufmann, Karla L. H. Feijs, and Bernhard Lüscher
Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-β1 mono-ADP-ribosylation by ARTD15
Maria Di Girolamo
Broadens your understanding of endogenous mono-ADP-ribosylation reactions
Brings together exciting recent findings on ADP-ribosylation
Written by leading experts in the field
Includes supplementary material: sn.pub/extras