Description
Folding for the Synapse, 2011
Coordinators: Wyttenbach Andreas, O'Connor Vincent
Language: EnglishSubjects for Folding for the Synapse:
Folding for the Synapse
Publication date: 11-2014
318 p. · 15.5x23.5 cm · Paperback
Publication date: 11-2014
318 p. · 15.5x23.5 cm · Paperback
Folding for the synapse
Publication date: 10-2010
318 p. · 15.5x23.5 cm · Hardback
Publication date: 10-2010
318 p. · 15.5x23.5 cm · Hardback
Description
/li>Contents
/li>Comment
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Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.
Introduction,- Protein Folding and Molecular Chaperones.- Transport of Proteins and Vesicles to the Synapse.- Protein Synthesis, Folding and Degradation in the Synaptic Compartment.- Synaptic Protein Interactions/Reguatlion by Molecular Chaperones.- Folding/Misfolding and Synaptic Dysfunction During Chronic Neurodegeration.
Introduces important concepts of folding machineries.
Gives examples of the biological relevance of further chaperone functions.
Addresses the current view on how protein folding and misfolding contribute to synapse function and dysfunction.
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