Histone Deacetylase Inhibitors as Cancer Therapeutics

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Language: English
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288 p. · 15x22.8 cm · Hardback

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics."

      1. Histone Deacetylase Inhibitors Disrupt the Mitotic Spindle Assembly Checkpoint by Targeting Histone and Non-Histone Proteins
      2. Mechanisms of Resistance to Histone Deacetylase Inhibitors
      3. HDAC Inhibitors: Roles of DNA Damage and Repair
      4. HDAC Inhibitor Modulation of Proteotoxicity as a Therapeutic Approach in Cancer
      5. Intrinsic and Extrinsic Apoptotic Pathway Signaling as Determinants of Histone Deacetylase Inhibitor Anti-Tumor Activity
      6. Histone Deacetylase Inhibitors and Rational Combination Therapies
      7. HDAC Inhibitors and Chaperone Function

       

Researchers and students in the basic and clinical sciences of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology, and molecular biology.
  • Provides invaluable information on the exciting and fast-moving field of cancer research
  • This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics"
  • Outstanding and original reviews