Immunology (8^th Ed.)
A Short Course

Immunology: A Short Course provides an overview of the physiology of the immune system and the pathophysiology of a broad range of immune-mediated diseases, offering accessible and comprehensive guidance to the basic concepts and clinical approaches in the discipline.

Now in its eighth edition, this bestselling textbook has been fully updated to reflect our expanded knowledge of how the immune system develops and functions, and the ways in which these physiological phenomena can fail or be compromised. New chapters examine cells and organs of the immune system, organization and expression of lymphocyte antigen receptor genes, experimental systems and methods, and B- and T-cell development activation. Helping students gain an integrated understanding of immunology, this textbook:

• Offers substantial new and revised material, expanded clinical coverage, enhanced pedagogical features, and updated figures, tables, and references
• Features recent research advances and therapeutic successes in the field of immunology
• Includes a companion website containing multiple choice questions, electronic flashcards, downloadable figures, PowerPoint slides, and sample cases
• Can be supplemented with the Clinical Cases in Immunology companion book 

The eighth edition of Immunology: A Short Course is an ideal resource for life and health science students, dental and nursing students seeking a short course text, and basic scientists and clinical researchers looking to refresh their knowledge in the subject. 

1 Overview of the Immune System 1

2 Cells and Tissues of the Immune System 13

3 Cells of the Innate Immunity 28

4 Complement 42

5 Immunogens and Antigens 58

6 Antibody Structure, Function, and Interactions with Antigen 70

7 Organization and Expression of Lymphocyte Antigen Receptor Genes 98

8 The Major Histocompatibility Complex and Antigen Presentation 116

9 B‐Cell Development and Activation 136

10 T‐Cell Development and Activation 154

11 Cytokines 191

12 Tolerance and Autoimmunity 209

13 Hypersensitivity: Type I 233

14 Hypersensitivity: Types II and III 249

15 Hypersensitivity: Type IV 259

16 Immunodeficiency Disorders and Neoplasias of the Lymphoid System 267

17 Transplantation 299

18 Tumor Immunology 313

19 Resistance and Immunization to Infectious Diseases 327

20 Experimental Systems and Methods 350

Richard Coico is Director of the Clinical and Translational Science Center and Professor of Cell Biology and Medicine in the College of Medicine, SUNY Downstate Health Sciences University in New York, USA. He is former President of the Association of Medical School Microbiology and Immunology Chairs (AMSMIC).