Description
Inhibitors of the Ras Superfamily G-proteins, Part B
Author: TAMANOI Fuyuhiko
Language: EnglishSubject for Inhibitors of the Ras Superfamily G-proteins, Part B:
Keywords
< p> Ras inhibitor; kinase; cancer; Raf; oncology; membrane association; non-oncogene addiction< /p>
280 p. · 15x22.8 cm · Hardback
Description
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Targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this is the second part of The Enzymes' volumes that discuss inhibitors of the Ras superfamily G-proteins.
- Discovery of Small-Molecule Ras Inhibitors that Display Anti-Tumor Activity by Interfering with Ras•GTP-Effector InteractionFumi Shima, Yoko Yoshikawa, Shigeyuki Matsumoto and Tohru Kataoka
- An Orthosteric Inhibitor of the RAS-SOS InteractionSeth Nickerson, Stephen T. Joy, Paramjit S. Arora and Dafna Bar-Sagi
- Conformation-Specific Inhibitors of Raf kinasesXiaolun Wang and Kristin Schleicher
- Inhibitors of the ERK Mitogen-activated Protein Kinase Cascade for Targeting RAS Mutant CancersLeanna Gentry, Ahmed A. Samatar and Channing J. Der
- Inhibiting the RAS - PI3K Pathway in Cancer TherapyClare Sheridan and Julian Downward
- The RalGEF/Ral Pathway: Evaluating an Intervention Opportunity for Ras CancersJonathan M. Cooper, Brian O. Bodemann and Michael A. White
- p21-Activated Kinase InhibitorsJoachim Rudolph, James J. Crawford, Klaus P. Hoeflich, and Jonathan Chernoff
- Recent Progress in Developing Small Molecule Inhibitors Designed to Interfere with Ras Membrane Association: Towards Inhibiting K-Ras and N-Ras Functions Fuyuhiko Tamanoi and Jie Lu
- Synthetic Lethal Genetic Screens in Ras Mutant CancersBing Yu and Ji Luo
Researchers in biochemistry, molecular and cell biology, pharmacology, and cancer
- Informs and updates on all the latest developments in the field
- Contributions from leading authorities and industry experts