Description
Insertional Mutagenesis Strategies in Cancer Genetics, 2011
Coordinators: Dupuy Adam J., Largaespada David A.
Language: EnglishSubjects for Insertional Mutagenesis Strategies in Cancer Genetics:
Publication date: 10-2014
200 p. · 15.5x23.5 cm · Paperback
Publication date: 11-2010
200 p. · 15.5x23.5 cm · Hardback
Description
/li>Contents
/li>Biography
/li>Comment
/li>
Adam Dupuy, Ph.D., is an Assistant Professor at the Carver College of Medicine at the University of Iowa, and a rising star in the field of insertional mutagenesis; two of the last of his publications have been in Nature, and he was the lead author on one of these. Dr. Dupuy earned his B.A. at Central College in Pella, Iowar, went on to earn his Ph.D. at the University of Minnesota in the Program in Molecular, Cellular, Developmental Biology & Genetics, and did his Postdoctoral fellowship in the Mouse Cancer Genetics Program at the NCI-Frederick.
This work summarizes the contribution that insertional mutagenesis has made to our understanding of cancer
A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms
The impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials
Includes supplementary material: sn.pub/extras