Managing the Older Adult Patient with HIV, 1st ed. 2016

Coordinators: Guaraldi Giovanni, Falutz Julian, Mussi Chiara, Silva Ana Rita

Language: English

52.74 €

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227 p. · 12.7x20.3 cm · Paperback
This concise, clinically focused pocket guide offers a complete overview of HIV in the older patient and reviews the latest guidelines, treatment options, clinical trials, and management of HIV within this subgroup. The easily accessible text offers infectious disease specialists and other health care professionals with an excellent quick reference tool, with full color tables and figures enhancing the text further. HIV is a chronic disease that affects the immune system, leading to AIDS. As treatments have progressed and patients with HIV are living longer a new aspect has to be taken in to consideration when treating HIV and other conditions. Comorbidities are rife within older adults with HIV, as many of the treatments for HIV cause long-term side effects, such as heart conditions and cancer. Special consideration must be taken to ensure no toxic drug-drug interactions between treatments.

1. Introduction

References

 

2. Pathophysiology of HIV/AIDS

Key points

2.1 Immunodeficiency, immune activation, and chronic inflammation

2.2 HIV and immunosenescence

2.3 Evolving clinical profile

References

 

3. HIV associated non-AIDS conditions in patients aging with HIV

Key points

3.1 HIV-associated non-AIDS conditions versus comorbidities

References

 

4. Comorbid conditions and older adults with HIV

Key points

4.1 Multimorbidity

4.2 Accentuated versus accelerated aging

4.3 Aging versus aged

References

 

5. Frailty in HIV

Key points

5.1 Defining frailty

5.2 Measuring frailty

5.3 The utility of measuring frailty

5.4 Frailty in the context of HIV

References

 

6. Disability

Key points

6.1 Overview

6.2 Functional impairment and disability in patients with HIV

6.3 Tools to measure disability

6.4 Conclusion

References

 

7. Geriatric syndromes

Key points

7.1 Definition

7.2 Falls

7.3. Delirium

7.4 Conclusion

References

 

8. HIV prevention and screening in older adults

Key points

8.1 Age-related risk factors

8.2. Barriers to prevention

8.3. Screening and counselling opportunities

References

 

9. Multidimensional geriatric assessment in older patients with HIV

Key points

References

 

10. Antiretroviral treatment in older patients

Key points

10.1 When to start antiretroviral therapy

10.2 What to start

10.3 What to change

10.4 Future perspectives

References

 

11. HIV, aging, and polypharmacy

Key points

References

 

12. Nutrition and physical exercise in older patients with HIV

Key points

12.1 Overview

12.2 Assessment of risk of malnutrition

12.3 Intervention

12.4 Sarcopenic obesity

12.5 Physical exercise

12.6 Conclusion

References

 

13. Smoking cessation in patients with HIV

Key points

13.1 Pharmacological strategies to treat nicotine dependence

References

 

14. Self-management

Key points

References 

Giovanni Guaraldi, MD, is Assistant Professor of Infectious disease at University of Modena and Reggio Emilia, Italy, where he also completed his medical training. Dr Guaraldi undertook his residency at Liverpool School of Tropical Medicine, UK, and Jackson Memorial Hospital, USA.

Dr Guaraldi was awarded the Dean's Delegate Cooperation for development projects of Modena University. He has extensive experience in HIV in resource limited countries and has coordinated the European Africa, Caribbean, Pacific project CoBaSys (Community Based System in HIV Treatment) focused on antiretroviral access programs in sub-Saharan African countries.

In 2002 Dr Guaraldi started a liver and kidney transplant program for people with HIV at the multivisceral transplant centre at Policlinico of Modena, Italy. Since the centre opened he has personally cared for approximately 80 patients with HIV who have received solid organ transplantation. Dr Guaraldi has lead the Modena HIV Metabolic Clinic since 2000. This referral centre cares for more than 4000 patients and offers a multidisciplinary team consisting of infectious disease physicians, nutritionists, occupational therapists, psychologists, cardiologists, nephrologists, endocrinologists, and plastic surgeons for the diagnosis and treatment of non-infectious comorbidities.

Dr Guaraldi has been the principal investigator in several studies generated by the MHMC, mainly focused on frailty and HIV associated comorbidities. He has extensive experience in scientific publication, with more than 260 peer reviewed papers, he is co-editor of Journal of Antimicrobial Chemotherapy, serves as reviewer for the major HIV journals, and as a consultant for EMA. He supervises PhD student in the Experimental Medicine PhD course at Modena University.

Dr Guaraldi is a panel member of the European AIDS Clinical Society guidelines on prevention and management of HIV associated comorbidities and has published widely

A concise, practical handbook on the care of older patients with HIV, covering the pathophysiology, diagnosis, treatment, and comorbidities associated with this disease

Reviews the current treatment guidelines and recommendations for management of HIV in this subset of patients, and discusses the emerging treatments suitable for comorbid patients

Easily accessible text, tables, and images provide readers with a fast synopsis of key studies and available treatment options