Membrane transporters as drug targets, Softcover reprint of the original 1st ed. 1999
Pharmaceutical Biotechnology Series, Vol. 12

Coordinators: Amidon Gordon L., Sadée Wolfgang

Language: Anglais

189.89 €

In Print (Delivery period: 15 days).

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Membrane Transporters as Drug Targets
Publication date:
530 p. · 15.5x23.5 cm · Paperback

Approximative price 439.00 €

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Membrane transporters as drug targets
Publication date:
544 p.
This volume focuses on recent advances in our understanding of the structure, function, physiologyr and molecular biology of membrane transporters. Emphasized topics include transporters as molecular targets for drug delivery and disposition in the body.
Overview of Membrane Transport.- Classification of Membrane Transporters.- Drug Transport and Targeting.- The Molecular Basis for Hepatobiliary Transport of Organic Cations and Organic Anions.- Affinity of Drugs to the Different Renal Transporters for Organic Anions and Organic Cations.- Drug Disposition and Targeting.- The Mammalian Facilitative Glucose Transporter (GLUT) Family.- Cationic Amino Acid Transporters (CATs).- Electrophysiological Analysis of Renal Na+-Coupled Divalent Anion Transporters.- Dipeptide Transporters.- Antigenic Peptide Transporter.- Nucleoside Transporters of Mammalian Cells.- Multidrug-Resistance Transporters.- Transporters for Bile Acids and Organic Anions.- Molecular and Functional Characteristics of Cloned Human Organic Cation Transporters.- Organic Anion Transporters.- Vitamin B12 Transporters.