Neuro-oncology
NIP- Neurology in Practice Series

Brain cancer is one of the most devastating diagnoses a physician can deliver. Cancer of the nervous system can take many different forms. Treatment is specific to the type of malignancy, its location in the nervous system and, increasingly, its molecular characteristics. The challenges manifest further when management choices need to be made, and multidisciplinary approaches are required. Additional complexities arise in children, where the developing neurological system requires more sensitive treatment.

Neuro-oncology unmasks the complexities to provide a straightforward guide to cancers of the nervous system. Following a general approach to diagnosis and treatment, the clinical aspects of specific cancer types in adults and children are explained in practical terms. A final section considers the effect of system cancer on the nervous system and the side effects of treatment.

Clinical in approach, practical in execution, Neuro-oncology will help you diagnose and manage your patients more effectively.

Neurology in Practice

Series Editors
Robert A Gross , MD, PhD, Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA
Jonathan W Mink, MD, PhD, Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA

The Neurology in Practice series provides clinical 'in the office' or 'at the bedside' guides to effective patient care for neurologists. The tone is practical, not academic, with authors offering guidance on what might be done and what should be avoided. The books are informed by evidence-based practice and feature:

• Algorithms and guidelines where they are appropriate
• 'Tips and Tricks' boxes ? hints on improving outcomes
• 'Caution' warning boxes ? hints on avoiding complications
• 'Science Revisited' ? quick reminder of the basic science principles
• Summaries of key evidence and suggestions for further reading

Foreword

Preface

Acknowledgements

Section I: Overview and General Aspects of Theory

1 Diagnosis of Brain Tumors: Clinical and Radiographic
Isabel Arrillaga-Romany, Eudocia Quant Lee and Patrick Y. Wen

2 Epidemiology and Etiology
Melissa L. Bondy, Yanhong Liu and Michael Scheurer

3 General Aspects of Surgery
Brian Williams, Robert Louis and Mark Shaffrey

4 General Approach to Radiation Oncology
Jennifer S. Yu and Daphne Haas-Kogan

5 General Aspects of Chemotherapy including "Biologic Agents"
Jethro Hu and Santosh Kesari

Section II: Adult Nervous System Tumors

6 Malignant Gliomas in Adulthood
Michael Ivan, Matthew Tate, and Jennifer Clarke

7 LGG and Oligodendrogliomas in Adulthood
Derek R Johnson and Kurt A. Jaeckle

8 Ependymomas
Kanwal P.S. Raghav and Mark Gilbert

9 Germ Cell Tumors and Other Pineal Region Tumors
Geneviève Legault and Jeffrey C. Allen

10 Sellar Tumors: Pituitary Adenomas and Craniopharyngiomas
Robert G. Louis and Robert Dallapiazza and John Jane Jr.

11 Meningiomas
Wendy Sherman and Jeffrey Raizer

12 Intradural Spinal Cord Tumors
Ben Shofty, Akiva Korn, Zvi Lidar and Shlomi Constantini

Section III: Pediatric Brain Tumors

13 Gliomas in Childhood
Bruce H. Cohen

14 Embryonal Tumors
Roger J. Packer

15 Infantile Brain Tumors
Alyssa Reddy

Section IV: Systemic Concerns to the CNS and Treatment Sequelea

16 Primary Central Nervous System Lymphomas
Jerome Graber and Antonio M.P. Omuro

17 Intracranial Metastases
Mary Welch and Thomas J. Kaley

18 Spinal Cord Compression
Melike Mut

19 Leptomeningeal Metastases
Sean Grimm and Marc Chamberlain

20 Immune Mediated Paraneoplastic Neurologic Disorders: An Overview
Myrna R. Rosenfeld and Josep Dalmau

21 Neurotoxicity of Radiation Therapy and Chemotherapy
Eudocia C. Quant Lee

David Schiff, MD, Departments of Neurology, Neurological Surgery, and Medicine, University of Virginia Health Science Center, Charlottesville, VA, USA