Neurovirology
Handbook of Clinical Neurology Series

Section 1 Introduction1. A history of viral infections of the central nervous system: Foundations, milestones, and patterns2. Basics of virology3. Neuroepidemiology and the epidemiology of viral infections of the nervous system4. Clinical approach to the syndromes of encephalitis, myelitis and meningitis5. Laboratory diagnosis of viral disease6. Neuroimaging of viral infections of the central nervous system7. Viral neuropathogenesis8. Neuropathology of viral infections9. Innate immune viral recognition: Relevance to CNS infections10. Adaptive immune response to viral infections in the central nervous systemSection 2 DNA viruses11. Herpes simplex virus12. Varicella zoster13. Epstein-Barr virus infections of the nervous system14. Cytomegalovirus infections of the adult human nervous system15. Congenital cytomegalovirus infection16. Human herpesvirus-6 and the nervous system17. Progressive multifocal leukoencephalopathySection 3 RNA viruses18. Enterovirus/picornavirus infections19. The equine encephalitides20. West Nile and St. Louis encephalitis viruses21. The Bunyaviridae22. Human endogenous retroviruses and the nervous system23. Central nervous system HIV-1 infection24. Neurological disease due to HTLV-1 infection25. Tick-borne encephalitis26. Japanese encephalitis virus infection27. Measles virus and the nervous system28. Mumps and rubella29. Rabies30. Neurologic aspects of influenza viruses31. Neurological complications of hepatic viruses32. Henipavirus encephalitis33. Diseases of the central nervous system caused by lymphocytic choriomeningitis virus and other arenavirusesSection 4 Other topics concerning viral or presumed viral infections of the CNS34. Nervous system viral infections in immunocompromised hosts35. Acute disseminated encephalomyelitis36. Vaccines and viral / toxin associated neurological infections37. Encephalitis lethargica (von Economo's encephalitis)38. Bell’s palsy and vestibular neuronitis

I graduated with a B Sc in physics from McGill University in Montreal in 1978. I obtained my PhD in physics from Brown University in 1983. After postdoctoral work at Purdue University, I entered medical school at the University of Miami in Florida, graduating with my MD in 1987. I trained in clinical neurology at Northwestern University and Duke University, followed by postdoctoral training in neurovirology at the University of Pennsylvania, 1991-1994. Since 1994 I have been on the faculty at the Department of Neurology at Wayne State University.
My laboratory work had been in the virology of the nervous system and in viral immunology with emphasis on the cytomegaloviruses. Clinically my interests had been in viral encephalitis, multiple sclerosis, and HIV of the nervous system. From 1993 until my retirement in 2005, I was the National Program Director for Neurology for the Department of Veterans Affairs. Our goal was to have neurological services coordinated nationally. During that time we were able to establish national centers of excellence for Parkinson’s Disease and Multiple Sclerosis. Just after my retirement, a coalition of organizations led by the American Academy of Neurology convinced the Congress to establish national VA centers of excellence in epilepsy. I am presently interested in historical subjects including historical virology: see for example To Catch a Virus, Booss and August, ASM Press, 2013; and Neurovirology in the Elsevier series Handbook of Clinical Neurology, eds, Tselis and Booss, forthcoming, 2014.