Principles of international endocrine practice. Measurement of circulating hormones. Standard protocols for endocrine emergencies. Standard protocols for diabetic emergencies. Endocrine autoimmunity. Endocrinology and evolution: the future of. Population endocrinology. Prevention in endocrinology (e.g. screening and iodine). Inherited susceptibility to endocrine and metabolic. Molecular biology for the endocrine clinician. Molecular aspects of hormonal regulation. Endocrine units. Diabetes centres (collaboration and improved results). Clinical physiology of the endocrine system. Clinical neuroendocrinology. Clinical anterior pituitary anatomy physiology. Genetic and acquired hypopituitarism. Glucocorticoid/thyroid/sex steroids. GH deficiency in adults and its treatment. Molecular pathogenesis of pituitary tumours. Clinically non-functioning pituitary tumours. Thyrotrophinomas. Pituitary incidentalomas. Pituitary carcinomas. Pituitary assessment strategy. Imaging of the pituitary and the hypothalamus. Histopathology of pituitary tumours. Transphenoidal surgery and other pituitary surgery. Pituitary radiotherapy. Prolactinomas. Acromegaly and gigantism. Cushing's disease (including children). Hypothalamic syndromes. Craniopharyngiomas. Cysts, hamartomas and vascular tumours. Perisellar tumours. Inflammatory lesions (sarcoid, histiocystosis etc.). Pineal pathophysiology : anatomy and physiology. Pineal pathophysiology : melatonin. Pineal tumours. Neuroendocrine dysfunction in anxiety/depression etc.. Endocrinology and alcoholism. Anorexia, bulimia and the neuroendocrinology of eating disorders. Pre-menstrual neuroendocrinology. Neuropsychoendocrinology : stress pains and opioids. Neuropsychoendorinology : sexual differentiation. Thyroid. Biosynthesis, transport, metabolism and actions. Clinical assessment of the thyroid patient. Thyroid function tests and effects of drugs. Non-thyroidal illness. Thyroid imaging : nuclear medicine techniques. Nonisotopic techniques for thyroid imaging. Epidemiology of thyroid disease and swelling. Genetic factors relating to the thyroid. Disorders of iodine deficiency. Disorders of iodine excess. Radiation induced thyroid disease. Autoimmune thyroid disease. Thyroiditis (acute, subacute, chronic, fibrosis). Clinical measurement and systemic manifestations. Management of thyrotoxicosis without hyperthyroidism. Thyrotoxic storm. Subclinical hyperthyroidism. Thyrotoxicosis and periodic paralysis. Causes and laboratory investigations of thyrotoxicosis. Radioiodine treatment of thyrotoxicosis. Surgery for thyrotoxicosis. Management of Grave's hyperthyroidism. Grave's ophthalmopathy. Management of toxic multinodular goitre and hypothyroidism. Clinical assessment and systemic manifestations of hypothyroidism. Causes and laboratory investigations of hypothyroidism. Treatment of hypothyroidism. Myxoedema coma. Subclinical hypothyroidism. Thyroid disease during pregnancy. Thyroid disease after pregnancy (postpartum thyroiditis). Thyroid disease in new-borns, infants and children. Thyroid hormone resistance syndrome. Pathogenesis of non-toxic goitre. Management of non-toxic goitre. Management of single thyroid nodule. Pathogenesis of thyroid cancer. Pathology of thyroid cancer. Papillary, follicular and anaplastic thyroid carcinoma. Medullary thyroid carcinoma. Parathyroid, calcium and bone metabolism. Osteoporosis. Thyroid disease and osteoporosis. Hypercalcaemic and hypocalcaemic syndromes. Hypercalcaemia. Parathyroid diseases (adenoma, hyperplasia etc). Familial hypocalciuric hypercalcaemia (FHH). Molecular genetics of disorder of calcium homeostasis. Hypoparathyroid and pseudohypoparathyroid disorders. Rickets and osteomalacia (inherited and acquired). Paget's disease. Bone dysplasias (including osteogenesis imperfecta). The adrenal gland. Molecular genetics of adrenal tumours. Addison's syndrome. CRF, ACTH and glucocorticoid resistance syndromes. Adrenal imaging. Adrenal surgery. Incidentalomas. Phaeochromocytomas and neuroblastomas. Primary hyperal.