Prodrug Design
Perspectives, Approaches and Applications in Medicinal Chemistry

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Language: English

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84 p. · 15x22.8 cm · Paperback

Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference.

1. Introduction: the drug discovery process, history and need of prodrug 2. Definition of Prodrug3. Types of Prodrugs 4. Approaches for Prodrugs5. Applications of Prodrug Design6. Role and Current Status of Prodrug Design in drug discovery 7. Available Prodrugs by Therapeutic Area

Medicinal and pharmaceutical chemistry researchers

Professor Redasani has 15 years experience of teaching medicinal chemistry for undergraduate and and graduate students, and is well versed with the need and changing scenario in the process of drug discovery. He’s actively involved in research, with a recent publication on Prodrugs in Eur. J. Medi. Chem. (2012).
Professor Bari is highly engaged in research on drug design, prodrugs, and computational chemistry with publications in high impact factor journals, four books, and 18 years of experience in the area.
  • Offers unique, detailed overview of Prodrug research and literature
  • Provides detailed chemical structures
  • Includes Prodrug listing by therapeutic area