Profiles of Drug Substances, Excipients and Related Methodology
Profiles of Drug Substances, Excipients and Related Methodology Series, Vol. 38

Coordinator: Brittain Harry G.

Language: Anglais
Cover of the book Profiles of Drug Substances, Excipients and Related Methodology

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528 p. · 15.2x22.9 cm · Hardback
Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic.

The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field
  1. Alendronate Sodium
  2. Gennady Ananchenko, Jasmina Novakovic, and Anna Tikhomirova

  3. Aripiprazole
  4. Febry Ardiana, Maria L.A.D. Lestari, and Gunawan Indrayanto

  5. Butyl Methoxy Dibenzoylmethane
  6. Jutta Kockler, Sherryl Robertson, Michael Oelgemöller, Murray Davies, Bruce Bowden, Harry G. Brittain, and Beverley D. Glass

  7. Carvedilol
  8. Kevin Beattie, Geeta Phadke, and Jasmina Novakovic

  9. Melatonin
  10. Fatmah A.M. Al-Omary

  11. Menadione
  12. Ghada S. Hassan

  13. Analytical Profile of Moxidectin
  14. Atul Awasthi, Majid Razzak, Raida Al-Kassas, Joanne Harvey, and Sanjay Garg

  15. Paroxetine Hydrochloride
  16. David Germann, George Ma, Feixue Han, and Anna Tikhomirova

  17. Paroxetine Hydrochloride: Polymorphs and Solvatomorphs
  18. Harry G. Brittain

  19. Sucralose
  20. Omar A.A. AlDeeb, Hoda Mahgoub, and Nagwa H. Foda

  21. Tramadol Hydrochloride Robert Smyj, Xiao-Ping Wang, and Feixue Han
Medicinal, pharmaceutical, and analytical chemists; pharmacologists
Dr. Brittain is presently the Institute Director of the Center for Pharmaceutical Physics, a research and consulting institute he established in 1999 for the study of substances having pharmaceutical interest. His research interest include all areas of pharmaceutical physics and physical pharmacy, including preformulation, formulation design, product characterization, polymorphism, solvatomorphism, and cocrystals of drug substances. Formerly, Dr. Brittain was Vice President for Pharmaceutical Development of Discovery Laboratories, Inc., he served as Director of Pharmaceutical Development at Ohmeda, Inc., and also led a variety of groups within the Analytical R&D department at Bristol-Myers Squibb.

Dr. Brittain is a graduate of Queens College (B.A. in chemistry, 1970; M.A. in physical chemistry 1972), and of the City University of New York (Ph.D. in physical chemistry, 1975). He was a postdoctoral fellow at the University of Virginia, and has held full-time faculty positions at Ferrum College (Assistant Professor of Chemistry) and Seton Hall University (Associate Professor of Physical and Inorganic Chemistry). He has been Adjunct Professor of Pharmaceutics at Rutgers University, and both Adjunct Professor of Chemistry and Visiting Research Scientist at Lehigh University.

Dr. Brittain has authored over 340 research publications and book chapters, and has presented over 175 invited lectures and short courses in the pharmaceutical field. He has edited the monographs Analytical Applications of Circular Dichroism, Physical Characterization of Pharmaceutical Solids, Polymorphism in Pharmaceutical Solids (first and second editions), Spectroscopy of Pharmaceutical Solids, and Preformulation in Solid Dosage Form Development. He is also the Editor-In-Chief of the book series Profiles of Drug Substances, Excipients, and Related Methodology, having edited 23 published volumes in the series that is now published annually by Elsevier. Dr. Brittain is also an Editor