Protein Targeting, Transport, and Translocation

Coordinators: Dalbey Ross, von Heijne Gunnar

Language: English
Cover of the book Protein Targeting, Transport, and Translocation

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336 p. · 15x22.8 cm · Hardback
Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.
Methods in Protein Targeting, Translocation and Transport
Targeting Sequences
Protein Export in Bacteria
Protein Sorting at the Membrane of the Endoplasmic Reticulum
Membrane Protein Insertion into Bacteial Membranes and Endoplasmic Reticulum
Disulfide Bond Formation in Prokaryotes and Eukaryotes
The Unfolded Protein Response
Protein Quality Control in the Export Pathway: The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection
Translocation of Proteins into Mitochondria
The Import and Sorting of Protein into Chloroplasts
Import of Proteins into Peroxisomes
Nucleocytoplasmic Transport
Protein Transport to the Yeast Vacuole
The Secretory Pathway
Vesicular Transport
Conclusion/Perspective
Researchers and graduate students in biochemistry, cell biology, molecular biology and biophysics.
  • Basic principles and techniques
  • Targeting adn sorting sequences
  • Protein export in bacteria
  • Membrane protein integration into ER and bacterial membranes
  • Protein translocation across the ER
  • Disulfide bond formation in prokaryotes and eukaryotes
  • Quality control in the export pathway
  • Import of proteins into organelles
  • The secretory pathway
  • Vesicular transport
  • Spectacular color throughout