Regulators and Effectors of Small GTPases: Rho Family
Author: BALCH W. E.Language: Anglais
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848 p. · Hardback
Since the last Methods in Enzymology volume on this topic in 2000, Rho GTPases have continued to receive a huge amount of attention. The human genome sequence has revealed the full extent of the Rho GEF and Rho GAP families (over 80 members for each) and the challenge of identifying the molecular interactions and cellular pathways influenced by each of these regulators is a daunting prospect. This new volume describes some of the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular level.
*Describes the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular levels.
*Includes new imaging techniques that revolutionize the ability to visualize GTPase activities.
*Over 150 international contributors.
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