Stem Cell Biology and Tissue Engineering in Dental Sciences

Coordinators: Vishwakarma Ajaykumar, Sharpe Paul, Shi Songtao, Ramalingam Murugan

Language: English
Cover of the book Stem Cell Biology and Tissue Engineering in Dental Sciences

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932 p. · 21.4x27.6 cm · Hardback

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences.  It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs.

Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues.  This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. 

Part 1: Developmental Biology: A Blueprint for Tissue Engineering
Part 2: In Vitro Regulation of Cell Behaviour and Tissue Development
Part 3: Biomaterials in Tissue Engineering
Part 4: Oral and Craniofacial Stem Cells for Tissue Engineering
Part 5: Tooth Tissue Engineering
Part 6: Tissue Engineering in Endodontics
Part 7: Periodontal Tissue Engineering
Part 8: Craniofacial Tissue Engineering
Part 9: Bioengineering Organs in Head and Neck
Part 10: Tissue Engineering Skin and Oral Mucosa
Part 11: Tissue Engineered Implant Dentistry
Part 12: Tissue Engineering in Orthodontics & Dentofacial Orthopedics
Part 13: Transplantation of Engineered Tissue Constructs
Part 14: Research Ethics and Law

Basic and clinical researchers in the fields of biomedical science, cell biology, nanoscience, nanotechnology, biomaterial science and engineering, bioengineering, and cell biology working within dental sciences research

Dr Ajay Vishwakarma is a researcher in the fields of stem cell bio-engineering, biomaterials, tissue engineering, cancer immunology and immuno-engineering; working with Division of Engineering in Medicine, Department of Medicine, at Brigham and Women’s Hospital, Harvard Medical School and an affiliate at the Harvard-MIT Division of Health Sciences and Technology at the Massachusetts Institute of Technology.
Dr Vishwakarma earned a Doctors degree in Dental Surgery at Maharashtra University of Health Sciences and Masters degree in Tissue Engineering at Cardiff University, UK where he primarily studied signaling pathways involved in musculoskeletal repair and regeneration. He continued mesenchymal stem cell and tissue-engineering research during his fellowship in the Khademhosseini laboratory at the Harvard-MIT Division of Health Sciences and Technology, USA. Currently he is pursuing a PhD in Cancer Biology with training in Cancer Immunology at the Carver College of Medicine, University of Iowa in Prof. Weizhou Zhang’s Laboratory, Department of Pathology, Holden Cancer Center wherein he is studying how regulatory T cells impact cancer progression and metastasis in humanized cancer models.
He was a recipient of a stem cell training fellowship from CCMB, a CSIR Indian institute, a graduate research fellowship by National Blood Foundation and National Cancer Institute government grant agencies. In addition to the long-term academic interest; he is committed to translating next generation cell-based therapies and has held key industrial positions in Europe and Asia. He is a co-founder of OCTE Technologies, a biotech start-up utilizing cell and tissue engineering technology platform to solve medical problems.
Professor Paul Sharpe is the Dickinson Professor of Craniofacial Biology at Kings College London. He graduated with a degree in biology from York University (1977) and a PhD in biochemistry from Sheffield University (1981). Following postdocs in Sheffield,
  • Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization
  • Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology
  • Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine
  • Print book is available and black and white, and the ebook is in full color