Structural Genomics, Part B
Advances in Protein Chemistry and Structural Biology Series, Vol. 76
Coordinator: Joachimiak AndrzejLanguage: Anglais
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450 p. · 15.2x22.9 cm · Hardback
While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.
*Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy
* Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission