The Duke Glioma Handbook
Pathology, Diagnosis, and Management

The management of patients with a glioma is challenging and best achieved by a team approach encompassing a combination of chemotherapy, radiotherapy, immunotherapy, and surgical excision in a specialist Cancer Center - the balance of treatment depending on the site and grade of tumor. Survival rates are improving and care of patients with or recovering from gliomas is increasingly handled in the community under the care of local physicians. This book provides an authoritative, multi-disciplinary summary of glioma biology, genetics, management and social issues, based on the world-leading program at the Duke University Preston Robert Tisch Brain Tumor Center, one of the world's largest and most successful Centers to offer brain cancer treatment and translational research. The text is written by specialists from this Center, giving it a consistent approach and style. This is an important educational resource for neurologists, neurosurgeons, oncologists, psychiatrists, neurohospitalists and ancillary members of neuro-oncology teams.

Preface; 1. Genetics of glioma Landon J. Hansen, Bill H. Diplas, Joseph Webb, Oren Becher and Hai Yan; 2. Glioma surgery Kyle G. Halvorson and Allan H. Friedman; 3. Radiation therapy for gliomas John P. Kirkpatrick, Grace Kim and John H. Sampson; 4. Chemotherapy for gliomas Annick Desjardins and Henry S. Friedman; 5. Immunotherapy for gliomas Peter E. Fecci, Katherine Riccione, Gavin P. Dunn, Elizabeth Reap, Gordana Vlahovic, Kendra Congdon and John H. Sampson; 6. Neuroradiology of gliomas Peter G. Kranz; 7. Neuropathology of gliomas Roger McLendon and Thomas J. Cummings; 8. Design and statistical analysis of clinical trials for glioma therapy James E. Herndon, II; 9. Health-related quality of life in glioma patients Katherine B. Peters; Index.

John H. Sampson is the Robert H. and Gloria Wilkins Professor of Neurosurgery, Chair of the Department of Neurosurgery, and Professor of Biomedical Engineering, Immunology, Pathology, and Radiation Oncology at Duke University Medical Center, Department of Neurosurgery, North Carolina.