The Mechanics of Inhaled Pharmaceutical Aerosols
Author: Finlay Warren H.Language: Anglais
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306 p. · 17.2x24.4 cm · Hardback
The book begins by providing a comprehensive introduction to aspects of aerosol mechanics that are relevant to inhaled pharmaceutical aerosols. It then gives an exhaustive pedagogical description of the behaviour of evaporating and condensing droplets (both aqueous and propellant-based), an introductory chapter on lung geometry and inhalation patterns, and coverage of relevant aspects of fluid mechanics in the lung. Finally, the book provides invaluable, detailed coverage on the mechanics of common pharmaceutical aerosol delivery systems and deposition in the respiratory tract. Throughout the book are many detailed numerical examples that apply the salient concepts to typical inhaled pharmaceutical aerosols.
This book will be of interest to scientists and engineers involved in the research and development of inhaled pharmaceutical aerosol products. Experienced practitioners will find many new perspectives that will greatly enhance their understanding of this complex and rapidly growing field. For those delivering therapeutic agents to the lung, this book is a must-have. Students and academics will find this book an invaluable tool and for newcomers it is a worthy guide to the diverse fields that must be understood to work in the area of inhaled pharmaceutical aerosols.
Particle Size Distributions
Motion of a Single Aerosol Particle in a Fluid
Particle Size Changes due to Evaporation or Condensation
Introduction to the Respiratory Tract
Fluid Dynamics in the Respiratory Tract
Particle Deposition in the Respiratory Tract
Dry Powder Inhalers
Metered Dose Propellant Inhalers