The NMDA receptor 2nd ed (paper) (2nd Ed.)

Coordinators: Collingridge G. L., Watkins J. C.

Language: Anglais
Cover of the book The NMDA receptor 2nd ed (paper)

Subjects for The NMDA receptor 2nd ed (paper)

Approximative price 224.70 €

Subject to availability at the publisher.

Add to cartAdd to cart
Publication date:
432 p. · 15.5x23.4 cm
Updates coverage on the NMDA receptor - a protein in the brain involved in the electrical and chemical processes which may underlie learning and memory. These receptors are also thought to contribute to stroke-induced brain damage and Alzheimer's disease.
2). Agonists and competitive antagonists: structure, activity and molecular modelling studies. 3). Non-competitive antagonists of N-methyl-D-aspartate. 4). Molecular pharmacology of NMDA receptors. 5). Molecular biology of NMDA receptors. 6). Anatomical, pharmacological, and molecular diversity of native NMDA receptor subtypes. 7). The NMDA receptor, its channel, and its modulation by glycine. 8). The time-course of NMDA receptor-mediated synaptic currents. 9). Activation of NMDA receptors. 10). NMDA receptors and their interactions with other excitatory amino acid receptors in synaptic transmission in the mammalian central nervous system. 11). The importance of NMDA receptors in the processing of spinal primary afferent input patterns. 12 ). The role of NMDA receptors in synaptic integration and the organization of motor patterns. 13). NMDA receptors and long-term potentiation in the hippocampus. 14). NMDA receptors and developmental plasticity in visual neocortex. 15). The role of NMDA receptors in learning and memory. 16). Clinical implications of NMDA receptors. 17). The NMDA receptor in epilepsy. 18). NMDA receptors, neuronal development, and neurodegeneration. 19). Competitive NMDA antagonists as drugs. 20). Non-competitive NMDA antagonists as drugs. 1). The NMDA receptor concept: origins and development.
'From reviews of the 1st edition:''a welcome text providing a wealth of up-to-date detail for a modest price. Not only the chemical and neuropharmaoological, but also the physiological, clinical neurological and neuropsychological aspects of the NMDA receptor are lucidly and succinctly dealt with. . . Unreservedly recommended reading.'' Journal of the Neurological Sciences'