The Pancreatic Beta Cell

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press.

The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones.  A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed.

This volume focuses on the pancreatic beta cell.

1. Metabolic Regulation of Insulin SecretionKevin Keane and Philip Newsholme
2. Proinsulin Entry and Transit through the Endoplasmic Reticulum in Pancreatic Beta CellsMing Liu, Jordan Wright, Huan Guo, Yi Xiong and Peter Arvan
3. Metabolism-Secretion Coupling and Mitochondrial Calcium Activities in Clonal Pancreatic Beta-CellsLukas N. Groschner, Muhammad Rizwan Alam and Wolfgang F. Graier
4. Metabolic Syndrome and Ionic Channels in Pancreatic Beta-CellsMarcia Hiriart, Myrian Velasco, Carlos Larqué and Carlos Manlio Diaz-Garcia
5. The Beta Cell ImmunopeptidomeNadine L. Dudek and Anthony W. Purcell
6. Autophagy and Pancreatic Beta CellsSimona Mazza and Tania Maffucci
7. The Somatostatin Receptor in Human Pancreatic ß-CellsMatthias Braun
8. Modulation of the Pancreatic Islet-Stress Axis as a Novel Potential Therapeutic Target in Diabetes MellitusBarbara Ludwig, Andreas Barthel, Andreas Reichel, Norman L. Block, Stefan Ludwig, Andrew V. Schally and Stefan R. Bornstein
9. Regenerative Medicine for Diabetes: Differentiation of Human Pluripotent Stem Cells into Functional ß Cells in Vitro and their Proposed Journey to Clinical TranslationBipasha Bose, Kishore Reddy Katikireddy and Sudheer Shenoy
10. The Calcium-Sensing Receptor and ß-Cell FunctionPaul E. Squires, Peter M. Jones, Mustafa Y.G. Younis and Claire E. Hills
11. Cellular Inhibitor of Apoptosis Protein-1 and Survival of Beta Cells Undergoing Endoplasmic Reticulum StressPu Xia and Yanfei Qi
12. ß-Cell Responses to Nitric OxideKatarzyna A. Broniowska, Bryndon J. Oleson and John A. Corbett
13. Activated Protein C and its Potential Applications in prevention of islet ß Cell Damage and DiabetesMeilang Xue and Christopher J. Jackson
14. Zinc and its Transporters, Pancreatic ß-Cells, and Insulin MetabolismLiping Huang
15. The NOTCH Pathway in ß-Cell Growth and DifferentiationYael Bar and Shimon Efrat
16. Roles of HNF1a and HNF4a in Pancreatic ß-Cells: Lessons from a Monogenic form of Diabetes (MODY)Kazuya Yamagata
17. Role of the Mammalian Target of Rapamycin (mTOR) Complexes in Pancreatic Beta Cell Mass RegulationAlberto Bartolome and Carlos Guillén

Researchers, faculty, and graduate students interested in cutting-edge review concerning the molecular and cellular biology of vitamins, hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry, molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested.

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)

• Expertise of the contributors
• Coverage of a vast array of subjects
• In depth current information at the molecular to the clinical levels
• Three-dimensional structures in color
• Elaborate signaling pathways