Description
Tumor Dormancy, Quiescence, and Senescence, Vol. 3, Softcover reprint of the original 1st ed. 2014
Aging, Cancer, and Noncancer Pathologies
Tumor Dormancy and Cellular Quiescence and Senescence Series, Vol. 3
Coordinator: Hayat M.A.
Language: EnglishSubject for Tumor Dormancy, Quiescence, and Senescence, Vol. 3:
Publication date: 08-2016
Support: Print on demand
Publication date: 09-2014
144 p. · 17.8x25.4 cm · Hardback
Description
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Preface
I. General Applications
1. Active, dormant, or on the path to elimination: what does a senescent cell do?
2. Hypoxia and tumor dormancy: can the two tango?
3. Progeriod syndromes: role of accelerated fibroblast senescence and p38 activation
4. Induction of cancer cells senescence: role of caffeic acid 3,4-dihydroxy-phenethyl ester
II. Role in breast cancer
5. Various factors contributing to tumor dormancy: therapeutic implications in breast cancer
6. Progression of hormone-dependent mammary tumors after dormancy: role of wnt pathway
III. Role in ovarian cancer
7. Chemoresistance, dormancy and recurrence in platinum drug therapy of ovarian cancers
8. The role of angiogenesis, growth arrest and autophagy in human ovarian cancer xenograft models for tumor dormancy
IV. Role in leukemia
9. Regulation of the promyelocytic leukemia protein and its role in premature senescence
V. Role in cardiovascular disease
10. Cardiac senescence and autophagy
Index.
Discusses the effects of senescence and dormancy in breast cancer, ovarian cancer and leukemia, as well as in cardiovascular diseases
Advances the body of knowledge of cancer cell regression, including possible use of pro senescence therapy as an alternative to surgery, chemotherapy or radiation therapy
Includes the contributions of some 26 experts representing seven different countries
Includes supplementary material: sn.pub/extras
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