Ubiquitin and Protein Degradation, Part B

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Language: Anglais

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952 p. · Hardback
Ubiquitin and Protein Degradation, Part B will cover chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. The chapters are highly methodological and focus on application of techniques.

*Second part of the Ubiquitin and Protein Degration series
*Topics include: E1 Enzymes, E2 Enzymes, E3 Enzymes, Proteasomes, and Isopeptidases
SECTION I. UBIQUITIN AND UBIQUITIN DERIVATIVES
SECTION II. UBIQUITIN-BINDING DOMAINS
SECTION III. METHODS TO STUDY THE PROTEASOME
SECTION IV. IDENTIFICATION AND CHARACTERIZATION OF SUBSTRATES AND UBIQUITIN LIGASES
SECTION V. GENOME- AND PROTEOME-WIDE APPROACHES TO IDENTIFY SUBSTRATES AND ENZYMES
SECTION VI. REAL TIME/NON-INVASIVE TECHNOLOGIES
SECTION VII. SMALL MOLECULE INHIBITORS
SECTION VIII. GENERALLY APPLICABLE TECHNOLOGIES