White Matter Injury in Stroke and CNS Disease, 2014
Springer Series in Translational Stroke Research Series, Vol. 4

1          White matter: Basic principles of axonal organization and function

Alexander A Velumian and Marina Samoilova

2          Electrophysiology evaluation of white matter injury           

Mingke Song, Anna Woodbury, Shanping Yu

3          CADASIL and animal models     

Francesco Blasi, PharmD, PhD, Anand Viswanathan, MD, PhD Cenk Ayata, MD

4          Neuroimaging of White Matter Injury: A Multimodal Approach to Vascular Disease  

Gary A. Rosenberg, Branko Huisa, Fakhreya Y. Jalal, Yi Yang

5          Diffusion MRI Biomarkers of White Matter Damage in Traumatic Brain Injury

Maria Ly, Samuel Ji, Michael A. Yassa

6          Mechanisms underlying the selective vulnerability of developing white matter

Paul A. Rosenberg

7          Neonatal experimental white matter injury     

Zhengwei Cai

8          Focal ischemic white matter injury in experimental models          

Robert Fern

9          Global ischemic white matter injury in patients        

Shinichi Nakao, Yan Xu

10        Experimental global ischemia and white matter injury       

Ji Hae Seo, Kazuhide Hayakawa, Nobukazu Miyamoto, Takakuni Maki, Loc-Duyen, Eng H. Lo, Ken Arai

11        White Matter Injury after Experimental Intracerebral Hemorrhage

Kenneth R. Wagner

12        White Matter Repair after Ischemic Injury       

Elif G Sӧzmen, S. Thomas Carmichael

13        White Matter Injury in Subarachnoid Hemorrhage in Humans

Gian Marco De Marchis, MD and Stephan A. Mayer, MD

14        Neurodegenerative diseases and white matter injury in patients            

George Bartzokis, M.D., Po H. Lu, Psy.D

15        Unmyelinated and myelinated axons exhibit differential injury and treatment response following traumatic brain injury

Thomas M. Reeves, Adele E. Doperalski, Linda L. Phillips

16        Age-Dependent Mechanisms Of White Matter Injury After Stroke           

Selva Baltan

17        White matter damage in multiple sclerosis    

María Victoria Sánchez-Gómez, Fernando Pérez-Cerdá, Carlos Matute

18        Calcium dyshomeostasis in white matter injury

Elena Alberdi, Asier Ruiz, Carlos Matute

19        Inflammation and white matter injury in animal models of ischemic stroke

Lyanne C. Schlichter, Sarah Hutchings, Starlee Lively

20        Oxidative stress in white matter injury  

Hideyuki Yoshioka, Takuma Wakai, Hiroyuki Kinouchi, Pak H Chan

21        Acute Axonal Injury in White Matter Stroke    

Jason D. Hinman, S. Thomas Carmichael

22        Mitochondria disorder and white matter injury         

R. Anne Stetler, PhD, Rehana K. Leak, PhD, Zheng Jing, PhD, Xiaoming Hu, PhD, Yanqin Gao, MD, Guodong Cao, PhD, and Jun Chen, MD

23        Heave metal and white matter injury    

Yang V. Li

24        Anesthesia and white matter injury

Phillip Vlisides, Zhongcong Xie

Selva Baltan, MD, PhD is an Associate Professor of Molecular Medicine at the Department of Neurosciences at the Cleveland Clinic. Her research focuses on mechanisms of brain cell damage following stroke in white matter in a region-specific and age-specific manner. Currently she is interested in the role of protein acetylation and mitochondrial dynamics in white matter stroke which has expanded her interests to neurodegenerative diseases such as Multiple Sclerosis and Alzheimer’s disease that involve white matter.

S. Thomas (Tom) Carmichael is a neurologist and neuroscientist in the Department of Neurology at the David Geffen School of Medicine at UCLA. Dr. Carmichael is Professor and Vice Chair in the Department, with active laboratory and clinical interests in stroke and neurorehabilitation and how the brain repairs from injury. He received his M.D. and Ph.D. degrees from Washington University School of Medicine in 1993 and 1994, and completed a Neurology residency at Washington University School of Medicine, serving as Chief Resident in 1997-1998. Dr. Carmichael was a Howard Hughes Medical Institute postdoctoral fellow at UCLA from 1998-2001, studying mechanisms of axonal sprouting, with a clinical emphasis on neurorehabilitation and stroke. He has been on the UCLA faculty since 2001. Dr. Carmichael’s laboratory studies the molecular and cellular mechanisms of neural repair after stroke and other forms of brain injury. This research focuses on the processes of axonal sprouting and neural stem cell and progenitor responses after stroke, and on neural stem cell transplantation. Dr. Carmichael is an attending physician on the Neurorehabilitation and Stroke clinical services at UCLA.

Dr. Carmichael has published important papers on stroke recovery that have defined mechanisms of plasticity and repair. These findings include the fact that the stroke produces stunned circuits that limit recovery, but can be restored to normal functioning wi

Provides systematic expert summaries of normal white matter morphology

Details white matter injury following stroke and other CNS injuries

Contains key notes and implementation advice from the experts