Applications of Heterocycles in the Design of Drugs and Agricultural Products

Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Chapters in this updated volume cover Hydroxy azoles as carboxylic acid bioisosteres, Cyclic sulfoxides and sulfones in drug design, Thiazoles and topological control in drug design, Applications of fused pyrrolidine [3.3.0] heterocycles in drug design, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines.

Because biology and organic chemistry increasingly intersect, the associated nomenclature is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

1. Hydroxy azoles as carboxylic acid bioisosteres Marco Lucio Lucio Lolli 2. Cyclic sulfoxides & sulfones in drug design Alicia Regueiro-Ren 3. Thiazoles and topological control in drug design Robert Reid 4. Applications of fused pyrrolidine [3.3.0] heterocycles in drug design Nicholas A. Meanwell 5. 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic Tracey Pirali 6. Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines David P. Rotella

• Considered the definitive serial in the field of heterocyclic chemistry
• Serves as the go-to reference for organic chemists, polymer chemists and biological scientists
• Provides the latest, comprehensive reviews written by established authorities in the field
• Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds