Description
Mechanochemical Organic Synthesis
Authors: Margetic Davor, Štrukil Vjekoslav
Language: EnglishSubject for Mechanochemical Organic Synthesis:
Keywords
(Thio)urea; 1; 2; 3-Triazoles; 1; 3-Dipolar cycloadditions; Amide; Ball mill; Boronic acid esters; Click reaction; Condensation reactions; Contamination from wear; Cycloaddition; Diels�Alder reaction; Esters; Ethers; Ex situ and in situ reaction monitoring; Experiments; Fullerenes; Graphene; Green chemistry; Grignard reaction; Halogenation; Heterocycles; Host�guest; Hydrogen bonding; IBX; Imine; Mechanochemistry; Metal-catalyzed couplings; Milling parameters; Nanocarbons; Nanotubes; Nitrogen heterocyle; Organic synthesis; Oxidation; Oxone; Peptide bond; Potassium permanganate; Reduction; Rotaxanes; Self-assembly; Sodium borohydride; Solid-state analysis; Undergraduate curriculum; Weak interactions; Wittig reaction
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Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency.
The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions) and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area.
Chapter 1. Practical Considerations in Mechanochemical Organic Synthesis
Chapter 2. Carbon–Carbon Bond- Forming Reactions
Chapter 3. Carbon–Nitrogen Bond-Formation Reactions
Chapter 4. Carbon—Oxygen and Other Bond-Formation Reactions
Chapter 5. Cycloaddition Reactions
Chapter 6. Oxidations and Reductions
Chapter 7. Applications of Ball Milling in Nanocarbon Material Synthesis
Chapter 8. Applications of Ball Milling in Supramolecular Chemistry
Chapter 9. Experiments for Introduction of Mechanochemistry in the Undergraduate Curriculum
Dr. Vjekoslav Štrukil is a research associate at the laboratory for Physical Organic Chemistry at Rudjer Boškovic Institute in Zagreb, Croatia. He obtained his B.Sc. (2005) and Ph.D. (2010) degrees from the Faculty of S
- Features cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions
- Integrates advances in green chemistry research into industrial applications and process development
- Focuses on designing techniques in organic synthesis directed toward mild reaction conditions
- Includes global coverage of mechanochemical synthetic protocols for the generation of organic compounds
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