Description
NMR Spectroscopy of Biological Solids
Coordinator: Ramamoorthy A.
Language: EnglishSubjects for NMR Spectroscopy of Biological Solids:
Keywords
Anisotropic Chemical Shielding; Chemical Shift Anisotropy; chemical; Dipolar Coupling; shift; Chemical Shift; dipolar; Solid State NMR Spectroscopy; coupling; Solid State NMR Experiment; anisotropic; Isotropic Chemical Shift; shifts; NMR Spectrum; pulse; Torsion Angles; sequence; Ma; magic-angle; Cross Peaks; spinning; Chemical Shielding Tensors; Ma Rate; Solid State NMR Spectrum; 15N Chemical Shift; CSA Tensor; Dipolar Recoupling; DQ Coherence; REDOR; Chemical Shielding; Sample Preparation; Resonance Assignments; Quadrupolar Nuclei; Peptide Plane; 23Na NMR
Publication date: 09-2019
· 15.6x23.4 cm · Paperback
Publication date: 09-2005
408 p. · 15.6x23.4 cm · Hardback
Description
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Over the past decade, a myriad of techniques have shown that solid-state nuclear magnetic resonance (NMR) can be used in a broad spectrum of applications with exceptionally impressive results. Solid-state NMR results can yield high-resolution details on the structure and function of many important biological solids, including viruses, fibril-forming molecules, and molecules embedded in the cell membrane.
Filling a void in the current literature, NMR Spectroscopy of Biological Solids examines all the recent developments, implementation, and interpretation of solid-state NMR experiments and the advantages of applying them to biological systems. The book emphasizes how these techniques can be used to realize the structure of non-crystalline systems of any size. It explains how these isotropic and anisotropic couplings interactions are used to determine atomic-level structures of biological molecules in a non-soluble state and extrapolate the three-dimensional structure of membrane proteins using magic-angle spinning (MAS). The book also focuses on the use of multidimensional solid-state NMR methods in the study of aligned systems to provide basic information about the mechanisms of action of a variety of biologically active molecules.
Addressing principles, methods, and applications, this book provides a critical selection of solid-state NMR methods for solving a wide range of practical problems that arise in both academic and industrial research of biomolecules in the solid state. NMR Spectroscopy of Biological Solids is a forward-thinking resource for students and researchers in analytical chemistry, bioengineering, material sciences, and structural genomics.
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