Practical Guide to ICP-MS (3^rd Ed.)
A Tutorial for Beginners, Third Edition
Practical Spectroscopy Series

Written by a field insider with over 20 years experience in product development, application support, and field marketing for an ICP-MS manufacturer, the third edition of Practical Guide to ICP-MS: A Tutorial for Beginners provides an updated reference that was written specifically with the novice in mind. It presents a compelling story about ICP-MS and what it has to offer, showing this powerful ultra trace-element technique in the way it was intended?a practical solution to real-world problems.

New to the third edition:

• New chapter: Emerging ICP-MS Application Areas ? covers the three most rapidly growing areas: analysis of flue gas desulfurization wastewaters, fully automated analysis of seawater samples using online chemistry procedures, and characterization of engineered nanoparticles
• Discussion of all the new technology commercialized since the second edition.
• An updated glossary of terms with more than 100 new entries
• Examination of nonstandard sampling accessories, which are important for enhancing the practical capabilities of ICP-MS
• Insight into additional applications in the environmental, clinical/biomedical, and food chemistry fields as well as new directives from the United States Pharmacopeia (USP) on determining impurities in pharmaceuticals and dietary supplements using Chapters <232>, <233> and <2232>
• Description of the most important analytical factors for selecting an ICP-MS system, taking into consideration more recent application demands

This reference describes the principles and application benefits of ICP-MS in a clear manner for laboratory managers, analytical chemists, and technicians who have limited knowledge of the technique. In addition, it offers much-needed guidance on how best to evaluate capabilities and compare with other trace element techniques when looking to purchase commercial ICP-MS instrumentation.

An Overview of ICP-MS. Principles of Ion Formation. Sample Introduction. Plasma Source. Interface Region. Ion-Focusing System. Mass Analyzers: Quadrupole Technology. Mass Analyzers: Double-Focusing Magnetic Sector Technology. Mass Analyzers: Time-of-Flight Technology. Mass Analyzers: Collision/Reaction Cell and Interface Technology. Ion Detectors. Peak Measurement Protocol. Methods of Quantitation. Review of Interferences. Sample Preparation. Routine Maintenance. Alternative Sample Introduction Techniques. Coupling ICP-MS with Chromatographic Techniques for Trace Element Speciation. Common ICP-MS Applications. Emerging ICP-MS Application Areas. Comparing ICP-MS with Other Atomic Spectroscopic Techniques. How to Select an ICP Mass Spectrometer: Some Important Analytical Considerations. Final Thoughts. Useful Contact Information. Glossary of ICP-MS Terms. References. Index.