The Neuroscience of Cocaine
Mechanisms and Treatment

Coordinator: Preedy Victor R

Language: English
Cover of the book The Neuroscience of Cocaine

Subjects for The Neuroscience of Cocaine

Keywords

11CABP688; 5-HT1B receptor; ADHD; ADME; AMPA; AP-1; Abuse; Acamprosate; Acetylation; Acetylcholine; Acid-sensing ion channels; Acquisition; Addiction; Addiction therapy; Adenosine; Adolescent; Adulterant; Agonist; Alcohol; Ambivalence; Aminorex; Analysis; Anatomical pathway; Animal models of addiction; Antagonist; Antipsychotics; Anxiety; Apoptosis; Appetite; Argonaute protein; Attention deficit hyperactivity disorder; Attentional bias; Atypical antipsychotics; Aversion; BDNF; Basal ganglia; Bed nucleus of the stria terminalis; Behavior; Behavioral sensitization; Bioenergetics; Bioinformatics; Biperiden; Blood; Blood concentrations; Books; Brain; Brain-derived neurotrophic factor; Brief intervention; Butyrylcholinesterase; CB2 receptor; CRF; Cannabinoid; Cannabis; Cell type-specific; Chromatography; Circadian rhythm; Clinical; Clinical comorbidities; Cluster headache; Cocaine; Cocaine addiction; Cocaine aversion; Cocaine deaths; Cocaine dependence; Cocaine hydrolase; Cocaine reward; Cocaine use disorder (CUD); Cocaine-induced disorders; Cocaine-induced headache; Cognition; Cognitive control; Cognitive function; Computational docking; Conditioned place preference; Conditioned stimuli; Corticosterone; Cortisol; Crack; Crack cocaine; Craving; D-serine; DNA binding domain; DNA demethylation; DNA methylation; DNA methyltransferase; Decision-making; Delay-discounting; Delta opioid receptor; DeltaFOSB; Demand; Disulfiram; Dopamine; Dopamine receptor; Dopamine receptors; Dopamine transporter; Dopaminergic differentiation; Dorsolateral striatum; Dorsomedial striatum; Drd1a-EGFP mice; Drug

173.83 €

In Print (Delivery period: 14 days).

Add to cartAdd to cart
Publication date:
Support: Print on demand

The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms.

Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine?s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse.

Part 1. Cocaine, Behavior, and Psychopathological Effects
Part 2. Effects of Cocaine Misuse on Neurological Function and Features
Part 3. Pharmacology and Neuropharmacology
Part 4. Withdrawal and Abstinence
Part 5. Cocaine as a Component of Dual-Use and Polydrug Use or Poly Addictions
Part 6. Cellular Effects and Molecular Biology of Cocaine
Part 7. Treatments for Cocaine Misuse and Dependency and Related Features
Researchers and advanced students in neuroscience, pharmacology, psychopathology, and addiction, as well as drug-abuse workers, public-health workers, and physicians treating addiction
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Illustrated in full color
  • Provides unique full coverage of all aspects of cocaine and its related pathology
  • Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms