Description
Cilia
Development and Disease
Coordinator: Goggolidou Paraskevi
Language: EnglishKeywords
Myosin Ic; ATII Cell; primary; Primary Cilia; motile; Sensenbrenner Syndrome; ciliary; Planar Cell Polarity Pathway; axoneme; Motile Cilia; signalling; ADPKD Patient; retinal; Hh Signalling; degeneration; Stereociliary Bundles; outer; IFT Complex; hair; Hair Cells; cells; PCD Patient; Gilbert Lauter; Non-canonical Wnt Signalling; Peter Swoboda; RPE; Isabel Tapia-P; Canonical Wnt Signalling; Laura L; Yates; Pcp Protein; Hannah M; Mitchison; Lca Patient; Charlotte H; Dean; Wnt Signalling; Sigolène M; Meilhac; Pcp Signalling; Jantje M; Gerdes; Eukaryotic Cilium; Miriam Schmidts; Kidney Morphogenesis; S; Patnaik; Ureteric Bud Branches; V; Kretschmer; Outer Hair Cells; H; May-Simera; ARPKD; Helen May-Simera; Autosomal Recessive Polycystic Kidney Disease
Publication date: 03-2021
· 15.6x23.4 cm · Paperback
Publication date: 04-2018
· 15.6x23.4 cm · Hardback
Description
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The scope of the book is to highlight the diverse roles of cilia in human development and disease. Almost all cell types form cilia and although they were first detected about 200 years ago, their significance was unclear. In the past ten years, it has become obvious that cilia have got sensory functions, as well as roles in motility and their mis-formation or the deregulation of the signaling pathways they control has been associated with defective development and human disease. Although research has concentrated on the role of the cilium in each organ, no effort has been made so far to bring all this information together and relate it to the various human diseases. This book aims to gather all the expertise that has been acquired on primary cilia and translate it into a medical and research context that will be of interest to postgraduate students, researchers, medics and scientists.
Cilia in the Brain – Development and Disease. Cilia in Lung Development and Disease. The Role of Cilia in Heart Development and Disease. Cilia in Kidney Development and Disease. The Role of Cilia in Pancreatic Development and Disease. The Role of Cilia in Skeletal Development and Disease. The Role of Cilia in Development and Disease of the Eye. The Role of Cilia in the Auditory System.
Paraskevi Goggolidou received her DPhil in Clinical Medical Sciences from the University of Oxford and her BSc in Molecular Genetics from King's College London. She is currently employed by The Open University and University College London. Dr. Goggolidou has contributed to ten publications.
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Cilia 118.25 €